Results 71 to 80 of about 1,253,107 (314)

Symptoms? Which Symptoms? Distorted Symptom Presentation and Its Detection

open access: yes
In this chapter, we elaborated on the two main forms of distorted symptom reporting: symptom over- and underreporting. In certain situations, individuals might exaggerate their symptoms. For instance, defendants facing legal issues may overstate their mental health problems.
Merckelbach, Harald, Boškovic, Irena
openaire   +1 more source

Symptom experience in Korean patients with liver cirrhosis

open access: yes, 2018
This study was done to examine the level of symptom experience, and symptom variation in relation to demographic and clinical variables, in Korean patients with liver cirrhosis (LC).
김옥수
core   +1 more source

Role of patient-reported outcomes in geriatric oncology research and patient care

open access: yesHolistic Integrative Oncology
Health-related quality of life (HRQOL) and daily functioning are central considerations for older adults with cancer. Attention to symptom burden, daily functioning, and HRQOL is imperative in this patient population to identify relevant research ...
Xin Shelley Wang, Charles S. Cleeland
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Managing symptoms in patients with advanced lung cancer during radiotherapy: results of a psychoeducational randomized controlled trial

open access: yes, 2011
Context. Breathlessness, fatigue, and anxiety are distressing symptoms for patients with advanced lung cancer. Usually managed as isolated symptoms, theyoften can occur simultaneously. Previous research often has addressed management of discrete symptoms
Alison Richardson   +5 more
core   +1 more source

Antagonism of β-klotho signaling by peptide 19 impairs wheel running in male mice and potentiates the cisplatin-induced decrease in wheel running

open access: yesFrontiers in Pharmacology
BackgroundCancer-related fatigue results from competition between the metabolic demands of the tumor and those of skeletal muscles. This competition leads to an energy metabolism deficit, which is worsened by the detrimental effects of cancer therapy on ...
Brandon M. Chelette   +6 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Creating and validating a patient-reported outcome instrument for women with vulvar neoplasia after surgical treatment : a mixed-methods project [PDF]

open access: yes, 2012
In vulvar neoplasia, substantial improvements in therapy and care have been attained during the last decades.1 Nevertheless even minor surgical interventions cause multiple symptoms and side effects that impact women’s quality of life.2 The term ...
Senn, Beate
core   +1 more source

Epidemiological and clinical characteristics of COVID-19 patients in Nantong, China

open access: yesJournal of Infection in Developing Countries, 2020
Introduction: COVID-19 is a newly emerging life-threatening respiratory disease caused by a newly identified coronavirus SARS-CoV-2. Methodology: We included 28 COVID-19 patients admitted to Nantong Third Hospital from January 23 to February 26, 2020.
Renfei Lu   +10 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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