Results 91 to 100 of about 1,117,489 (293)

Symptom-based clusters in people with post-COVID-19 condition (PCC)

Journal of Translational Medicine
Background Identifying symptom clusters in post-COVID-19 condition (PCC) is a necessary step toward for developing more targeted therapeutic interventions for this heterogeneous condition. Therefore, the aim of this study was to identify symptom clusters
Charlotte Kuczyk, Christoph Herrmann-Lingen, Maike Stolz, Christian Krauth, Birte Burger, Jona Theodor Stahmeyer, Mariel Nöhre, Aline Debener, Christopher Käufer, Franziska Richter, Carlotta Derad, Martin Hellmich, Martina de Zwaan   +12 more
doaj   +1 more source

Cancer-Related Symptom Clusters, Eosinophils, and Survival in Hepatobiliary Cancer: An Exploratory Study

, 2010
The study of symptom clusters is gaining increased attention in the field of oncology in an attempt to improve the quality of life of patients diagnosed with cancer.
Olek, Marion C, Gamblin, T. Clark, Carr, Brian I, Antoni, Michael H, Mark L. Unruh, Brian I. Carr, T. Clark Gamblin, Geller, David A, Butterfield, Lisa H, Dew, Mary Amanda, Unruh, Mark L, David A. Geller, Steel, Jennifer L, Jennifer L. Steel, Marion C. Olek, Mary Amanda Dew, Michael H. Antoni, Kevin H. Kim, Kim, Kevin H, Lisa H. Butterfield   +19 more
core   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Correlation study of discomfort symptom clusters and self-management in patients with knee osteoarthritis: a cross-sectional study

BMC Geriatrics
Background This study aimed to explore the relationship between knee discomfort symptom clusters and self-management in old patients with knee osteoarthritis(KOA), providing a basis for clinical improvement of patient symptoms and self-management ...
Yabin Guo, Peipei Zhao, Biyun Zeng, Yang Zhou   +3 more
doaj   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

Symptoms and factors associated with symptom clusters among older adults with oral and oropharyngeal cancers at diagnosis

, 2021
OBJECTIVE: Describe differences in pretreatment symptoms and the composition of symptom clusters in older patients with oral and oropharyngeal cancer. METHODS: In this cross-sectional study, quality of life (QoL) assessments for cancer patients (EORCT ...
Silva,Ana Catarina Alves e, Mattos,Inês Echenique, Carmo,Cleber Nascimento do, Santos,Izabella Costa, Ana Catarina Alves e Silva, Cleber Nascimento do Carmo, Izabella Costa Santos, Inês Echenique Mattos   +7 more
core   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Exploring psychological symptom associations among people living with HIV using an apriori algorithm

BMC Infectious Diseases
Background Although antiretroviral therapy has extended the lifespan of people living with HIV (PLWH), psychological symptoms are still prevalent. Given the complexity of psychological symptoms, effective interventions need to consider the interactions ...
Jingxian Hu, Jiayun Zhou, Shuyu Han, Yuhua Li, Xin Xie, Dongxia Wu, Xiaolan Wang, Huimin Guo, Lili Zhang   +8 more
doaj   +1 more source

Atrial fibrillation symptom clusters [PDF]

, 2016
Background: Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. The majority of adults with AF are symptomatic, and symptoms are major determinants of quality-of-life.
Streur, Megan M, Streur, Megan M.
core