Results 231 to 240 of about 1,117,489 (293)

PLXDC2 siRNA‐Mediated Intervention Attenuates Microglial Senescence Through cGAS‐STING Signaling

open access: yesAdvanced Science, EarlyView.
PLXDC2 was identified as a microglial target in Parkinson's disease through human and mouse single‐cell analyses. Ferritin‐armed biomimetic nanovesicles delivered PLXDC2 siRNA, deferoxamine, and CeO2 nanoparticles across the blood–brain barrier, reducing cGAS‐STING activation, iron burden, oxidative stress, and senescence in microglia, thereby ...
Heyue Lu   +13 more
wiley   +1 more source

SAT1‐Induced Spermidine Depletion Potentiates Food Allergy

open access: yesAdvanced Science, EarlyView.
Spermidine depletion, driven by upregulated spermidine/spermine N1‐acetyltransferase (SAT1), potentiates food allergy by promoting mast cell degranulation through autophagy suppression. SAT1 physically interacts with the long noncoding RNA Cdk19os to inhibit Atg5 and Atg7, disrupting autophagic flux.
Manman Liu   +8 more
wiley   +1 more source

Phenotyping Pediatric Long COVID: Symptom Clusters from a Longitudinal Multicenter Italian Cohort. [PDF]

open access: yesChildren (Basel)
Esposito SMR   +22 more
europepmc   +1 more source

Differential contributions of PTSD symptom clusters and their associations with resilience in traumatized individuals with a refugee background. [PDF]

open access: yesEur J Psychotraumatol
Amiri MA   +6 more
europepmc   +1 more source

Characterizing symptom clusters for older adults with urinary incontinence in home healthcare. [PDF]

open access: yesGeriatr Nurs
Scharp D   +5 more
europepmc   +1 more source

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