Results 41 to 50 of about 1,117,489 (293)

Identifying central symptom clusters and correlates among post-COVID-19 pulmonary fibrosis patients: a network analysis

Frontiers in Medicine
BackgroundPrevious studies have analyzed symptom clusters in patients with coronavirus disease 2019 (COVID-19); however, evidence regarding the core symptom clusters and their influencing factors in patients with post-COVID-19 pulmonary fibrosis (PCPF ...
Zhen Yang, Zhen Yang, Zhiqin Xie, Zequan Wang, Zequan Wang, Linxia Yi, Linxia Yi, Shihan Chen, Shihan Chen, Yunyu Du, Xuemei Tao, Xuemei Tao, Chao Xie, Chao Xie, Li Zhou, Min Zhang, Chaozhu He   +16 more
doaj   +1 more source

Differences in composition of symptom clusters between older and younger oncology patients [PDF]

, 2015
Context\ud \ud Older oncology patients have unique needs associated with the many physical, psychological,and social changes associated with the aging process.
Cooper, Bruce A, Ritchie, C, Dunn, L, Skerman, Helen, Paul, Steven M, Skerman, H, Ritchie, Christine, Cataldo, JK, Yates, P, Aouizerat, Bradley, Alexander, K, Paul, Steven M., Alexander, Kimberly, Yates, Patsy, Cataldo, Janine K., Cataldo, Janine K, McCarthy, Alexandra, Dunn, Laura, Cooper, Bruce A., Paul, SM, McCarthy, A, Aouizerat, B, Cooper, BA, Miaskowski, Christine, Miaskowski, C   +24 more
core   +1 more source

HIV Symptom Clusters are Similar Using the Dimensions of Symptom Occurrence and Distress [PDF]

, 2022
CONTEXT: People living with HIV infection (PLWH) in the United States continue to experience a high symptom burden despite improvements in antiretroviral therapy.
Wilson, Natalie L, Saag, Michael S, Hoffman, Thomas J, Miaskowski, Christine, Heath, Sonya L, Sonya L. Heath, Michael S. Saag, Wilson, Natalie L., Christine Miaskowski, Heath, Sonya L., Saag, Michael S., Thomas J. Hoffman, Hoffman, Thomas J., Natalie L. Wilson   +13 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Symptom Clusters in Patients Receiving Chemotherapy: A Systematic Review [PDF]

, 2021
BACKGROUND AND PURPOSE: Since 2001, symptom cluster research has grown considerably. However, because multiple methodological considerations remain, ongoing synthesis of the literature is needed to identify gaps in this area of symptom science.
Harris, Carolyn S, Dhruva, Anand A, Kober, Kord M, Hammer, Marilyn J, Conley, Yvette P, Miaskowski, Christine A, Harris, Carolyn S., Conley, Yvette P., Carolyn S. Harris, Christine A Miaskowski, Miaskowski, Christine A., Dhruva, Anand A., Kober, Kord M., Anand A. Dhruva, Yvette P. Conley, Hammer, Marilyn, Kord M. Kober, Marilyn J. Hammer   +17 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Longitudinal relationships between posttraumatic stress symptoms and sleep problems in adolescent survivors following the Wenchuan earthquake in China. [PDF]

PLoS ONE, 2014
To examine the longitudinal relationships between Posttraumatic Stress Disorder (PTSD) and sleep problems among adolescent survivors in the Wenchuan earthquake, China.350 adolescent survivors were randomly selected from several primary and secondary ...
Xiao Zhou, Xinchun Wu, Yuanyuan An, Fang Fu   +3 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Differences in symptom clusters based on multidimensional symptom experience and symptom burden in stroke patients

Scientific Reports
In the study of stroke symptoms, a significant unresolved issue remains: What are the similarities and differences in the use of three symptom dimensions—occurrence, severity, and distress—and symptom burden to identify symptom clusters, and which level ...
Siyu Zhou, Dan Yin, Huijuan He, Mengying Li, Yuan Zhang, Jie Xiao, Xiangrong Wang, Lin Li, Dan Yang   +8 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source