Results 131 to 140 of about 2,054,384 (304)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Prolonged Shedding of Human Parechovirus in Feces of Young Children after Symptomatic Infection

, 2016
After symptomatic human parechovirus (HPeV) infection in infants, the duration of (mostly asymptomatic) shedding in feces was 2-24 weeks (median 58 days). HPeV cycle threshold value could neither differentiate between symptomatic disease and asymptomatic
Benschop, Kimberley S M, Wolthers, Katja C, Pajkrt, Dasja, Bouma-de Jongh, Saskia, Wildenbeest, Joanne G   +4 more
core  

Beta2-microglobulina en líquido cefalorraquídeo de recién nacidos con infección congénita sintomática por citomegalovirus: Un indicador certero de la gravedad de la afectación del sistema nervioso central [PDF]

, 2011
Introducción. En los neonatos con infección congénita sintomática por citomegalovirus (CMV) la neuroimagen es la mejor herramienta disponible para predecir la evolución neurológica a largo plazo.
Alarcón Allen, Ana
core  

Analysis of dengue infection and inapparent to symptomatic case ratios among cluster contacts by select characteristics in Zhongshan, Guangdong Province, China, 2013.

, 2015
NA: confidence interval not calculatedAnalysis of dengue infection and inapparent to symptomatic case ratios among cluster contacts by select characteristics in Zhongshan, Guangdong Province, China, 2013.
Yong-zhuang Cen (715562), Hunter R. Merrill (715564), Le Luo (277248), Benjamin D. Anderson (511336), Jia-hai Lu (715565), Bo Shu (270045), Tao Wang (12008), Man Wang (110466), Xue-qin Chen (5662855), Jin-yu Wang (5662858), Mary M. Merrill (715563)   +10 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Narrowing of T-cell receptor beta variable repertoire during symptomatic herpesvirus infection in transplant patients

, 2009
Primary infection or recrudescence of latent virus infection in transplant recipients can be manifested either as asymptomatic or symptomatic disease.
Denis J Moss, Sharon L Silins, Tania Crough, Rajiv Khanna, Khanna, Rajiv, Keith McNeil, McNeil, Keith, Campbell, Scott, Wynn, Katherine K., Moss, Denis J., Crough, Tania, Scott Campbell, Bell, Scott, Scott Bell, Silins, Sharon L., Andrew Galbraith, Galbraith, Andrew, Katherine K Wynn   +17 more
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

SARS-CoV-2 SPIKE Antibody Levels can Indicate Immuno-Resilience to Re-infection: a Real-World Study

Infectious Diseases and Therapy
Introduction The use of antibody titers against SARS-CoV-2, as a method of estimating subsequent infection following infection or vaccination, is unclear.
Yue Jin, Fei Yang, Christopher M. Rank, Stanley Letovsky, Peter Ramge, Simon Jochum   +5 more
doaj   +1 more source

COVID-19 vaccine effectiveness against symptomatic infection and hospitalisation in Belgium, July 2021 to May 2022. [PDF]

Euro Surveill, 2023
Braeye T, van Loenhout JAF, Brondeel R, Stouten V, Hubin P, Billuart M, Chung PYJ, Vandromme M, Wyndham-Thomas C, Blot K, Catteau L.   +10 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source