A Rigid Supramolecular Solution to a Flexible Problem: A Multifunctional Calix[4]arene-Based Strategy to Prevent α‑Synuclein Toxicity. [PDF]
Dell'Accantera D +7 more
europepmc +1 more source
Synthesis and Structure of an S‐Shaped Double Expanded Helicene With Seven Fused Anthracene Units
The anthracene‐fused aromatic compound was synthesized by four‐fold cycloisomerization of the corresponding alkyne precursor. X‐ray crystallographic analysis revealed that this compound had a double helical structure of Ci symmetry, in which the terminal and central anthracene units were triply stacked.
Shinji Toyota +6 more
wiley +1 more source
Protocol for using an ELISA to detect total α-synuclein levels in Drosophila melanogaster lines expressing human α-synuclein point mutations. [PDF]
Sciortino M +3 more
europepmc +1 more source
This research presents a novel 1,4‐π‐functionalized calix[6]arene with enhanced interactions with dialkylammonium axles. We investigate threading behavior in CDCl3, highlighting how exo‐rim π‐functionalization affects binding affinity and stereoselectivity.
Veronica Iuliano +7 more
wiley +1 more source
Effects of α-synuclein pathology on synaptic dysfunction and clinical outcomes in normal aging. [PDF]
Winer JR +22 more
europepmc +1 more source
N─H or O─H Bond Activation With a Bicyclic Si4 Ring Compound
The bicyclic Si4 ring compound with zwitterionic character reacts with NH3, H2O, and selected alcohols to give functionalized saturated silicon rings, siliconoid clusters with unsubstituted Si atoms, or simple 1,3‐addition products. The experimentally observed reactivity could be rationalized based on results from mechanistic calculations employing ...
Michael Quest +7 more
wiley +1 more source
STIP1/HOP promotes the formation of cytotoxic α-synuclein oligomers. [PDF]
Rutledge BS +11 more
europepmc +1 more source
First Operation Results of a Methanol Demonstration Plant With Real Steel Mill Gases
A demonstration plant with industrial setup regarding length, diameter, boiling water cooling system and gas recycle was initially operated with cleaned blast furnace gas and compared with earlier experiments with bottle gases. Dynamic disturbances from the steel mill and gas cleaning unit were noticed and could be compensated by the control system ...
Johannes Michael Voß, Tim Schulzke
wiley +1 more source
Bio inspired assessment of titanium-organic framework and exosome-constructed p-Synephrine carriage: pursuing the PI3K/mTOR pathway in a simulated periodontitis. [PDF]
Kishta MS +5 more
europepmc +1 more source
Sensitive LC‐HRMS methods were established for the detection of kisspeptin and its analogues in serum and urine, alongside their analytical and metabolic characterization. Stability studies were conducted in serum, plasma, and urine, highlighting the importance of appropriate sample handling for reliable anti‐doping analysis.
Sophia Krombholz +3 more
wiley +1 more source

