Results 121 to 130 of about 189,179 (323)
Abnormal Morphology and Synaptogenic Signaling in Astrocytes Following Prenatal Opioid Exposure
CellsIn recent decades, there has been a dramatic rise in the rates of children being born after in utero exposure to drugs of abuse, particularly opioids. Opioids have been shown to have detrimental effects on neurons and glia in the central nervous system ...
Ethan B. Niebergall +7 more
doaj +1 more source
Expression of Neurofilament Subunits at Neocortical Glutamatergic and GABAergic Synapses
Frontiers in Neuroanatomy, 2018 Neurofilaments (NFs) are neuron-specific heteropolymers that have long been considered as structural proteins. However, it has recently been documented that they may play a functional role at synapses.
Luca Bragina +3 more
doaj +1 more source
Synapse: Synthetic Application Profiler and Emulator [PDF]
2016 IEEE International Parallel and Distributed Processing
Symposium Workshops, Chicago, IL, USA, May 23-27, 2016, 2015 We introduce Synapse motivated by the needs to estimate and emulate workload execution characteristics on high-performance and distributed heterogeneous resources. Synapse has a platform independent application profiler, and the ability to emulate profiled workloads on a variety of heterogeneous resources.
arxiv
Emerging Therapeutic Strategies for Hearing Loss
Advanced Therapeutics, EarlyView.Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han +9 more
wiley +1 more source
The FGFR inhibitor Rogaratinib reduces microglia reactivity and synaptic loss in TBI
Frontiers in ImmunologyBackgroundTraumatic brain injury (TBI) induces an acute reactive state of microglia, which contribute to secondary injury processes through phagocytic activity and release of cytokines.
Rida Rehman +11 more
doaj +1 more source
The structures of the glia and of the synapses in the sympathetic chain of man [PDF]
, 1960 Katja Scharenberg
openalex +1 more source
Advanced Science, EarlyView.Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu +12 more
wiley +1 more source
陆军军医大学学报Objective To investigate the effects of adenovirus-associated virus (AAV)-mediated overexpression of LINGO-1 in the hippocampus on spatial learning and memory abilities, as well as the volume and Spinophilin+ dendritic spines of different subregions ...
WANG Shun, JIANG Lin, HE Qi
doaj +1 more source
Point Neurons with Conductance-Based Synapses in the Neural Engineering Framework [PDF]
arXiv, 2017 The mathematical model underlying the Neural Engineering Framework (NEF) expresses neuronal input as a linear combination of synaptic currents. However, in biology, synapses are not perfect current sources and are thus nonlinear. Detailed synapse models are based on channel conductances instead of currents, which require independent handling of ...
arxiv