Results 101 to 110 of about 214,710 (317)

Information architecture for a federated health record server [PDF]

open access: yes, 2002
This paper describes the information models that have been used to implement a federated health record server and to deploy it in a live clinical setting.
Patterson, D   +5 more
core  

Convergence of stochastic learning in perceptrons with binary synapses [PDF]

open access: yes, 2005
The efficacy of a biological synapse is naturally bounded, and at some resolution, and is discrete at the latest level of single vesicles. The finite number of synaptic states dramatically reduce the storage capacity of a network when online learning is ...
Senn, Walter, Fusi, Stefano
core   +1 more source

Room‐Temperature Skyrmionic Synapse in 2D Ferromagnet Fe3GaTe2 Operating via Collective Spin Texture Transformation

open access: yesAdvanced Materials, EarlyView.
We demonstrate a neuromorphic synapse in 2D Fe3GaTe2 flakes. The device operates via a current‐driven transformation from a skyrmion‐lattice to a stripe‐domain state, yielding a linear anomalous Hall resistance response with a tunable slope to enable multiply‐accumulate operations. Simulations confirm its viability in artificial neural networks.
Jixiang Huang   +20 more
wiley   +1 more source

Synapses immunologiques et synapses neuronales [PDF]

open access: yes, 2003
Les systèmes nerveux et immunitaire ont en commun de constituer dans l’organisme des réseaux complexes de cellules en interaction. Dans ces réseaux transitent en permanence d’énormes quantités d’informations, codées de façon très différente dans les deux
Revy, Patrick   +7 more
core   +1 more source

Projections from thalamic nucleus reuniens to hippocampal CA1 area participate in context fear extinction by affecting extinction-induced molecular remodeling of excitatory synapses

open access: yeseLife
The ability to extinguish contextual fear in a changing environment is crucial for animal survival. Recent data support the role of the thalamic nucleus reuniens (RE) and its projections to the dorsal hippocampal CA1 area (RE→dCA1) in this process ...
Magdalena Ziółkowska   +7 more
doaj   +1 more source

cAMP-Inhibits Cytoplasmic Phospholipase A2 and Protects Neurons against Amyloid-β-Induced Synapse Damage

open access: yesBiology, 2015
A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate
Clive Bate, Alun Williams
doaj   +1 more source

Deconstructing the synapse

open access: yesNature Neuroscience, 2018
While the role of protein synthesis in synaptic plasticity and memory is well-established, protein degradation processes have been less studied. A seminal 2003 Nature Neuroscience paper showed that ubiquitin-dependent degradation of synaptic proteins is engaged during activity-regulated synaptic remodeling.
openaire   +3 more sources

Proteomics of synapse [PDF]

open access: yesAnalytical and Bioanalytical Chemistry, 2006
Large-scale phosphoproteome analysis on synaptosome and preparation of post-synaptic density (PSD) were investigated. It was found that protein phosphor is a common event in the synapse, which is consistent with the presence of diverse classes of kinases and phosphatases in the synapse.
openaire   +3 more sources

Optimal Control Drives Ultrafast and Energy‐Efficient Magnetization Switching in Van der Waals Magnets

open access: yesAdvanced Materials, EarlyView.
ABSTRACT The accelerating expansion of data‐centric technologies is sharply increasing the energy burden of information storage, placing unprecedented pressure on the efficiency of magnetic switching. Conventional field‐driven reversal, once the foundation of magnetic memory, has become impractical in modern architectures due to its high energy cost ...
Mohammad H. Badarneh   +2 more
wiley   +1 more source

Neuromorphic Electronics for Intelligence Everywhere: Emerging Devices, Flexible Platforms, and Scalable System Architectures

open access: yesAdvanced Materials, EarlyView.
The perspective presents an integrated view of neuromorphic technologies, from device physics to real‐time applicability, while highlighting the necessity of full‐stack co‐optimization. By outlining practical hardware‐level strategies to exploit device behavior and mitigate non‐idealities, it shows pathways for building efficient, scalable, and ...
Kapil Bhardwaj   +8 more
wiley   +1 more source

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