Results 171 to 180 of about 187,009 (324)

Utilizing Caenorhabditis Elegans as a Rapid and Precise Model for Assessing Amphetamine‐Type Stimulants: A Novel Approach to Evaluating New Psychoactive Substances Activity and Mechanisms

Advanced Science, EarlyView.
This study uses Caenorhabditis elegans to assess the activity of amphetamine‐type stimulants (ATS) and their analogs. The research highlights the roles of dopamine and serotonin pathways, distinguishes chiral forms of ATS, and identifies structure‐activity relationships. These findings provide a rapid and cost‐effective model for evaluating the effects
Yuanpeng Li, Hongyuan Li, Hongshuang Wang, Xiaohui Wang   +3 more
wiley   +1 more source

Implementing Multimodal Hardware Security with 2D α‐In2Se3 Ferroelectric Transistor

Advanced Science, EarlyView.
A multimodal secure transistor‐integrated in‐memory sensing and computing architecture is demonstrated by leveraging its electronic and optoelectronic synaptic behaviors. Key security primitives, such as anticounterfeiting, watermarking, logic locking, and camouflaging, are implemented within a compact single‐transistor structure, providing a scalable ...
Xinwei Zhang, Jiachao Zhou, Yishu Zhang, Jian Chai, Yongqing Bai, Hailiang Wang, Qian He, Xi Wang, Lin Wang, Yuda Zhao, Yang Xu, Bin Yu   +11 more
wiley   +1 more source

Advances in the pathogenesis of Rett syndrome using cell models

Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 532-541, December 2022., 2022
Most Rett syndrome (RTT) patients are affected by the MECP2 gene mutations. And the mutations of MECP2 have wide effects on different cell types of nervous system, including neurons, astrocytes, oligodendrocytes and microglia, which always combined together to lead to abnormalities in the whole neural network.
Sijia Lu, Yongchang Chen, Zhengbo Wang
wiley   +1 more source

The Locus Coeruleus‐Periaqueductal Gray GABAergic Projection Regulates Comorbid Pain and Depression

Advanced Science, EarlyView.
LC‐GABA neurons exhibit elevated activity to noxious and aversive stimuli in chronic pain, and their activation alleviates pain‐ and depression‐like behaviors. While LC‐GABA neurons target LC‐NA neurons and GABA and Glu neurons in the vlPAG, they modulate the pain responses of LC‐NA neurons but regulate pain‐ and depression‐like behaviors through their
Yuan Gao, Xue Zhang, Xiao‐Juan Liu, Yi‐Ling Sun, Cui Yin, Dong‐Liang Tang, Cheng Xiao, Chunyi Zhou   +7 more
wiley   +1 more source

SYNAPSES IN THE RAT AND PIGEON MEDIAN EMINENCES

, 1967
Hideshi Kobayashi, Tokuzo Matsui
openalex   +2 more sources

Highly Robust Double Memristive Device Based on Perovskite/Molybdenum Oxide‐Sulfide Compound Heterojunction System

Advanced Electronic Materials, EarlyView.
A highly robust double memristor based on a molybdenum oxide‐molybdenum sulfide/perovskite heterojunction is demonstrated. Good resistive switching behavior with an endurance of 100 cycles, high retention of 2·× 104 s, and ON/OFF ratio of ≈102 is reported to emulate successfully the biosynapse's behavior.
Gion Kalemai, Apostolos Verykios, Georgios Chatzigiannakis, Polychronis Tsipas, Athanasios Dimoulas, Vassilis Psycharis, Elias Sakellis, Nikos Boukos, Vlassis Likodimos, Ioannis Karatasios, Michael‐Alexandros Kourtis, Konstantinos Aidinis, Alexander Chroneos, Abd Rashid bin Mohd Yusoff, Panagiotis Argitis, Dimitris Davazoglou, Maria Vasilopoulou, Anastasia Soultati   +17 more
wiley   +1 more source

Ferroelectric‐Assisted Ion Dynamics for Prolonged Tactile Cognizance in a Biomimetic Memory‐in‐Sensor System

Advanced Electronic Materials, EarlyView.
A promising mechanoreceptor‐inspired tactile memory‐in‐sensor (TMIS) device is reported, utilizing ferroelectric‐assisted ion dynamics in a synaptic tactile transistor (FAID‐STT). This design enhances long‐term tactile memory while minimizing power consumption in a unified TMIS device.
Ritamay Bhunia, Joo Sung Kim, Hayoung Oh, Dong Jun Kim, Seokyeong Lee, Cheolmin Park, Do Hwan Kim   +6 more
wiley   +1 more source

Molecular and Anatomical Strengthening of "Winner" Climbing Fiber Synapses in Developing Mouse Purkinje Cells. [PDF]

J Neurosci
Nitta A, Yamasaki M, Miyazaki T, Konno K, Yoshimura H, Watanabe M.   +5 more
europepmc   +1 more source

Properties of regenerating neuromuscular synapses in the frog

, 1960
Ricardo Miledi
openalex   +2 more sources

In‐Sensor Computing‐Based Smart Sensing Architecture Implemented Using a Dual‐Gate Metal‐Oxide Thin‐Film Transistor Technology

Advanced Electronic Materials, EarlyView.
A smart sensor architecture combining an array of sensing elements with an overlapping array of computing and memory elements thus emulates an innervated peripheral sensing system (IPSS) capable of local and autonomous neuromorphic in‐sensor data pre‐processing is presented. Compatibility of the proposed architecture with functionally distinct elements
Tengteng Lei, Yushen Hu, Xinying Xie, Runxiao Shi, Man Wong   +4 more
wiley   +1 more source