Results 261 to 270 of about 187,009 (324)

Amyloid-β-Driven Synaptic Deficits Are Mediated by Synaptic Removal of GluA3-Containing AMPA Receptors. [PDF]

J Neurosci
Reinders NR, van der Spek SJF, Klaassen RV, Koymans KJ, MacGillavry HD, Smit AB, Kessels HW.   +6 more
europepmc   +1 more source

An Optoelectronic Memristor Based on Proton‐Involved Photoreduction for Bimodal Sensing, Memory, and Processing

Advanced Intelligent Systems, EarlyView.
In this study, an optoelectronic memristor with integrated light/humidity bimodal sensing, memory, and processing functionalities is proposed. A proof of concept sensory–motion system with attention‐driven and relative humidity‐modulated behaviors is presented by sending the synaptic feedback of the memristor to a robot arm.
Qiaoling Tian, Xinyu Sui, Xiaoning Zhao, Ya Lin, Zhongqiang Wang, Ye Tao, Haiyang Xu, Yichun Liu   +7 more
wiley   +1 more source

Connectomic analysis of taste circuits in Drosophila. [PDF]

Sci Rep
Walker SR, Peña-Garcia M, Devineni AV.
europepmc   +1 more source

Compound Heterozygous Variants in ZSWIM7 Gene Linked to Infertility and Its Role in Gonadal Development

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT This study aims to elucidate the role of the ZSWIM7 gene in the etiology of infertility, focusing on its potential association with premature ovarian insufficiency and azoospermia. We investigated an 18‐year‐old female patient who presented with primary amenorrhea, hypoplasia of the uterus and ovaries, Tanner stage II breast and pubic hair ...
Denise M. Christofolini, Guilherme Pinn, Thainá Vilella, Maria I. Melaragno, Mariana Moysés‐Oliveira, Luciano Pompei, Rare Genomes Project Consortium, Bianca Bianco, Caio P. Barbosa   +8 more
wiley   +1 more source

The tau isoform 1N4R confers vulnerability of MAPT knockout human iPSC‐derived neurons to amyloid beta and phosphorylated tau‐induced neuronal dysfunction

Alzheimer's &Dementia, EarlyView.
Abstract INTRODUCTION Human tau protein, composed of six brain‐specific isoforms, is a major driver of Alzheimer's disease (AD). The role of its isoforms however remains unclear and human AD models are scarce. METHODS We generated human MAPT– (tau–) knockout (KO) induced pluripotent stem cells (iPSC) using CRISPR/Cas9, differentiated these into ...
Sarah Buchholz, Mohamed Aghyad Al Kabbani, Michael Bell‐Simons, Lena Kluge, Cagla Cagmak, Jennifer Klimek, Natja Haag, Lukas C. Iohan, Audrey Coulon, Marcos R. Costa, Devrim Kilinc, Hans Zempel   +11 more
wiley   +1 more source

Sleep need driven oscillation of glutamate synaptic phenotype. [PDF]

Elife
Vogt KE, Kulkarni A, Pandey R, Dehnad M, Konopka G, Greene RW.   +5 more
europepmc   +1 more source

GluN2B-mediated regulation of silent synapses for receptor specification and addiction memory. [PDF]

Exp Mol Med
Kim HJ, Lee S, Kim GH, Sung K, Yoo T, Pyo JH, Jo HJ, Lee S, Lee HY, Jung JH, Lee KJ, Kim JH.   +11 more
europepmc   +1 more source

Structural heterogeneity and subcellular distribution of nicotinic synapse-associated proteins.

, 1981
Reinhard Gysin, M. Wirth, Steven D. Flanagan   +2 more
openalex   +1 more source

Effects of Qingyangshen glycosides on neuroplasticity in a mouse model of social defeat

Animal Models and Experimental Medicine, EarlyView.
Summary of the experimental effects of qingyangshen glycosides on neuroplasticity in mice model of social defeat. Abstract Background Qingyangshen (Cynanchum otophyllum C.K. Schneid) is a folk drug for treating depression and other mental disorders induced by social defeat stress.
Jingru Wang, Weishi Chen, Qiang Zhu, Yao Liu, Zheng Kang, Dingding Liu, Guirong Zeng   +6 more
wiley   +1 more source

Astrocyte-secreted factors modulate synaptic protein synthesis as revealed by puromycin labeling of isolated synaptosomes. [PDF]

Front Mol Neurosci
de la Cruz-Gambra A, Baleriola J.
europepmc   +1 more source