Results 141 to 150 of about 10,129 (257)

Genetic and epigenetic insights into non-obstructive azoospermia: mechanisms, biomarkers, and clinical perspectives. [PDF]

Reprod Biol Endocrinol
Wang X, Nie L, Hong Z, Li L, Fan Q, Ma B, Li Z, Gao Y, Zhang M, Zhang Y, Wang M.   +10 more
europepmc   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

HSF5: A novel switch for meiotic pachynema progression in male germ cells. [PDF]

Genes Dis
Luo C, Yu Z, Liu D, Xu H, Zhan J, Sun F.
europepmc   +1 more source

Infrared Machine Vision System Based on Te NWs‐Au NPs Plasmonic Optoelectronic Memristor for Motion Detection

Advanced Science, EarlyView.
A plasmonic optoelectronic memristor based on Te nanowires‐Au nanoparticles/ι‐carrageenan enables IR‐programmed and visiblelight‐erased non‐volatile conductance. The all‐photonic write/erase scheme supports in‐sensor logic and real‐time motion detection in darkness.
Jingyao Bian, Yongxing Zhu, Ye Tao, Zhongqiang Wang, Xiaoning Zhao, Ya Lin, Haiyang Xu, Yichun Liu   +7 more
wiley   +1 more source

Mechanism and potential therapeutic strategies of genetic abnormalities involved in deoxyribonucleic acid double-strand breaks leading to the development of human non-obstructive azoospermia. [PDF]

Reprod Biol Endocrinol
Wang X, Zhang Y, Zhu Z, Wang C, Yao M, Xu H, Zhang Z, Ping H, Xia X, Meng K, Gao F, Yuan J.   +11 more
europepmc   +1 more source

Memristive Baffle Systems: Design, Simulation, and Applications

Advanced Science, EarlyView.
This study presents a nanoscale baffle‐system strategy for HfO2‐based memristors that controls oxygen‐vacancy transport through Al2O3 interlayers. Guided by multiscale simulation and experimental validation, the Al2O3 dual‐barrier configuration simultaneously enhances synaptic linearity and endurance.
Eun Young Kim, Juseong Park, Sumin Ju, Taeyoung Jeong, Dohyun Kim, Woojoon Park, Myeongchan Ko, Woon Hyung Cheong, Jung‐Hae Choi, Kyung Min Kim   +9 more
wiley   +1 more source

Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease

Advanced Science, EarlyView.
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang, Yuting Liu, Shufan Jiang, Zilin Fang, Mengda Jiang, Xiaofeng Tao, Tianyi Zhu, Jipeng Li, Sijie Fang, Xuefei Song, Yinwei Li, Jing Sun, Chuanjun Tong, Zhengrun Gao, Huifang Zhou, Xianqun Fan   +15 more
wiley   +1 more source

Genomic introgressions from wild relatives in the wheat genome alter meiotic dynamics in inter-varietal hybrids. [PDF]

Plant J
Yan L, Chéron F, Nadaud I, Hao M, Liu D, Sourdille P.   +5 more
europepmc   +1 more source

Water‐Assisted Exfoliation of HfO2‐Based Membrane for Flexible Robust Ferroelectric Synaptic Transistors

Advanced Science, EarlyView.
A flexible freestanding HfO2‐based ferroelectric membrane is achieved via a water‐assisted exfoliation technique using a Sr4Al2O₇ sacrificial layer. The BaTiO3/Hf0.5Zr0.5O2/BaTiO3 heterostructure maintains robust ferroelectricity and exhibits reliable synaptic plasticity.
Han Zhang, Miao Zeng, Jingxin Chen, Lei Wang, Sai Jiang, Qian Cao, Xuebo Li, Zekun Hou, Chun Shen, Yulin Gan, Ning Fang, Zhaoliang Liao, Ziyao Zhou, Lin Hao   +13 more
wiley   +1 more source

Protecting double Holliday junctions ensures crossing over during meiosis. [PDF]

Nature
Tang S, Hariri S, Bohn R, McCarthy JE, Koo J, Pourhosseinzadeh M, Nguyen E, Liu N, Ma C, Lu H, Lee M, Hunter N.   +11 more
europepmc   +1 more source