Results 171 to 180 of about 26,216 (365)

Mouse MutS-like protein Msh5 is required for proper chromosome synapsis in male and female meiosis [PDF]

, 1999
Sandra S. de Vries, Esther B. Baart, Marleen Dekker, A. Siezen, Dirk G. de Rooij, P. de Boer, Hein te Riele   +6 more
openalex   +1 more source

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

Advanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li, Zhuowen Hao, Fangzi Ke, Zhihui Liu, Weilong Wang, Sihui Wen, Fan Wu, Bowen Xu, Miao He, Shengyu Zou, Xiong Chen, Jingfeng Li, Zuhong He   +12 more
wiley   +1 more source

Nicking is asynchronous and stimulated by synapsis in 12/23 rule-regulated V(D)J cleavage [PDF]

, 1997
Quinn Eastman, David G. Schatz
openalex   +1 more source

NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea

Advanced Science, EarlyView.
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi, Zejun Gao, Yang Qiu, Renfeng Wang, Keyong Tian, Bo Yue, Xinyu Zhang, Peng Zhang, Ziqi Wu, Qingwen Zhu, Zhenzhen Liu, Zhuoyao Ma, Xueying Zhou, Yu Han, Jun Chen, Jianhua Qiu, DingJun Zha   +16 more
wiley   +1 more source

A defect in synapsis causes male sterility in a T‐DNA‐tagged Arabidopsis thaliana mutant [PDF]

, 1997
Brenda N. Peirson, Sarah Bowling, Christopher A. Makaroff   +2 more
openalex   +1 more source

Stabilizing synapsis [PDF]

Nature Chemical Biology, 2018
openaire   +2 more sources

Consequences and Mechanisms of Noise‐Induced Cochlear Synaptopathy and Hidden Hearing Loss, With Focuses on Signal Perception in Noise and Temporal Processing

Advanced Science, EarlyView.
Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley   +1 more source

The Mouse Spo11 Gene Is Required for Meiotic Chromosome Synapsis [PDF]

, 2000
Peter Romanienko, R. Daniel Camerini‐Otero   +1 more
openalex   +1 more source

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

Advanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du, Jun Huang, Aizhen Zhang, Fangfang Zhao, Tianwen Chen, Quinn M. McDermott, Tony Zheng, Haibo Wang, Rongli Zhang, Xiaolin Zhang, Jerome Allison, Hong Zhu, Wu Zhou, Qing Yin Zheng   +13 more
wiley   +1 more source

Synapsis strnadi Kral 2002

, 2012
Synapsis strnadi Král, 2002 Synapsis strnadi Král, 2002: 283, Figs. 1, 4, 7. The holotype is deposited in NMPC (ex coll. D. Král): HOLOTYPE (♀): ‘ VIETNAM N. / Tam Dao - 900 m / 16.-23. V. 1991 / Strnad Jan lgt. [p] // Synapsis / strnadi sp. n. ♀ / HOLOTYPUS / David Král det. 2002 [p, red label]’. Current status. Valid species.
Bezděk, Aleš, Hájek, Jiří, Ascr, Biology Centre   +2 more
openaire   +1 more source