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Genetic and epigenetic insights into non-obstructive azoospermia: mechanisms, biomarkers, and clinical perspectives. [PDF]
Wang X +10 more
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Synapsis and recombination in inversion heterozygotes
Inversion heterozygotes are expected to suffer from reduced fertility and a high incidence of chromosomally unbalanced gametes due to recombination within the inverted region. Non-homologous synapsis of the inverted regions can prevent recombination there and diminish the deleterious effects of inversion heterozygosity.
Anna A, Torgasheva, Pavel M, Borodin
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Chromosome synapsis in hexaploids
Journal of Theoretical Biology, 1980Abstract Theoretical relationships between pachytene multivalent and bivalent frequencies in hexaploids are deduced from a model, based on chromosomes showing sequential association at equidistant pairing sites and uniform propensities for partner exchange throughout their lengths.
R S, Callow, I, Gladwell
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On transmission of information by synapsis
International Journal of Bio-Medical Computing, 1970Abstract This study is a solution to a problem of information transmission by synapsis which is reduced to the integration of the equation with partial derivatives of the heat type with mixed conditions. The solution z(x, t) found is represented by an integral of Fourier series which tends to a singular integral in the neighbourhood of x = 0+, the
Badescu, R., Balaceanu, C., Nicolau, E.
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Sex-specific telomere redistribution and synapsis initiationin cattle oogenesis [PDF]
The process of homolog pairing is well characterised in meiosis of male mammals, but much less information is available from female meiosis. We have therefore studied telomere dynamics by FISH and synapsis formation by immunostaining of synaptonemal ...
Preben D Thomsen
exaly +2 more sources
Science, 2005
The complex mechanics of the eukaryotic cell cycle is monitored at a number of points to ensure that everything is going according to plan before the next step in the process is executed. Known checkpoints include DNA replication, DNA damage, and spindle function. Bhalla and Dernburg identify a checkpoint that monitors synapsis, or pairing
openaire +2 more sources
The complex mechanics of the eukaryotic cell cycle is monitored at a number of points to ensure that everything is going according to plan before the next step in the process is executed. Known checkpoints include DNA replication, DNA damage, and spindle function. Bhalla and Dernburg identify a checkpoint that monitors synapsis, or pairing
openaire +2 more sources
Chromosome rotation and formation of synapsis
Nature, 1976ALTHOUGH the rotation and oscillation of the nuclei of cultured spermatocytes have been known for some years1,2, no correlations of this phenomenon with the stages of mitosis or meiosis, or with the biochemical or cytogenetic events during germ-cell development have been made.
M, Parvinen, K O, Söderström
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Nature Genetics, 2005
The XY chromosome pair in mammalian males is sequestered into a transcriptionally dormant chromatin domain before the first meiotic division. New work shows that all chromosomes can suffer the same fate if they don't pair during meiosis, and that this may be part of a surveillance mechanism to protect against aneuploid gametes.
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The XY chromosome pair in mammalian males is sequestered into a transcriptionally dormant chromatin domain before the first meiotic division. New work shows that all chromosomes can suffer the same fate if they don't pair during meiosis, and that this may be part of a surveillance mechanism to protect against aneuploid gametes.
openaire +1 more source

