Results 81 to 90 of about 26,734 (323)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Failure of homologous synapsis and sex-specific reproduction problems

Frontiers in Genetics, 2012
The prophase of meiosis I ensures the correct segregation of chromosomes to each daughter cell. This includes the pairing, synapsis and recombination of homologous chromosomes. A subset of chromosomal abnormalities, including translocation and inversion,
Hiroki eKurahashi, Hiroshi eKogo, Makiko eTsutsumi, Hidehito eInagaki, Tamae eOhye   +4 more
doaj   +1 more source

The conserved AAA ATPase PCH-2 distributes its regulation of meiotic prophase events through multiple meiotic HORMADs in C. elegans.

PLoS Genetics, 2023
During meiotic prophase, the essential events of homolog pairing, synapsis, and recombination are coordinated with meiotic progression to promote fidelity and prevent aneuploidy.
Anna E Russo, Stefani Giacopazzi, Alison Deshong, Malaika Menon, Valery Ortiz, Kaori M Ego, Kevin D Corbett, Needhi Bhalla   +7 more
doaj   +1 more source

Location and Identification on Chromosome 3B of Bread Wheat of Genes Affecting Chiasma Number

Plants, 2022
Understanding meiotic crossover (CO) variation in crops like bread wheat (Triticum aestivum L.) is necessary as COs are essential to create new, original and powerful combinations of genes for traits of agronomical interest.
Benoit Darrier, Isabelle Colas, Hélène Rimbert, Frédéric Choulet, Jeanne Bazile, Aurélien Sortais, Eric Jenczewski, Pierre Sourdille   +7 more
doaj   +1 more source

Telomeres cluster de novo before the initiation of synapsis: a three-dimensional spatial analysis of telomere positions before and during meiotic prophase. [PDF]

, 1997
We have analyzed the progressive changes in the spatial distribution of telomeres during meiosis using three-dimensional, high resolution fluorescence microscopy.
Agard, DA, Bass, HW, Cande, WZ, Marshall, WF, Sedat, JW   +4 more
core  

Mimicking Synaptic Plasticity: Optoionic MoS2 Memory Powered by Biopolymer Hydrogels as a Dynamic Cations Reservoir

Advanced Functional Materials, EarlyView.
Janus (MoS2) transistors functionalized with sodium alginate (SA) and poly(vinylidene fluoride‐co‐trifluoroethylene) [P(VDF‐TrFE)] exhibit persistent photo‐induced ionic gating, driven by dynamic cation migration at the hybrid interface. This ionic mechanism enables finely tunable photoconductivity and emulates key synaptic plasticity behaviors ...
Yeonsu Jeong, Pietro Tordi, Adrián Tamayo, Bin Han, Massimo Bonini, Paolo Samorì   +5 more
wiley   +1 more source

Gated rotation mechanism of site-specific recombination by ϕC31 integrase [PDF]

, 2012
Integrases, such as that of the Streptomyces temperate bacteriophage ϕC31, promote site-specific recombination between DNA sequences in the bacteriophage and bacterial genomes to integrate or excise the phage DNA.
A. R. McEwan, Brown, D. E. Buck, Dhar, Dhar, F. J. Olorunniji, Ghosh, Grainge, Grindley, Heichman, Kanaar, Khaleel, Kilbride, M. C. M. Smith, Rowland, S. D. Colloms, S. J. Rosser, Smith, Smith, Smith, Stark, Stark, Stark, Stark, Stark, Thorpe, W. M. Stark, Wasserman, Yuan   +28 more
core   +1 more source

Genome-Wide Transcription During Early Wheat Meiosis Is Independent of Synapsis, Ploidy Level, and the Ph1 Locus

bioRxiv, 2018
Polyploidization is a fundamental process in plant evolution. One of the biggest challenges faced by a new polyploid is meiosis, particularly discriminating between multiple related chromosomes so that only homologous chromosomes synapse and recombine to
Azahara C. Martín, P. Borrill, J. Higgins, A. Alabdullah, R. Ramirez-Gonzalez, D. Swarbreck, C. Uauy, P. Shaw, G. Moore   +8 more
semanticscholar   +1 more source

Polaronic and Electrochemical Signatures in Group IVB (Ti, Zr, Hf) Oxides: Unified SKP–DFT Insights for Tunable Transport in Energy and Electronic Devices

Advanced Functional Materials, EarlyView.
Charge carrier concentration and mobility in TiO2, ZrO2, and HfO2 powder films are experimentally mapped as a function of temperature. The results uncover polaron‐mediated transport regimes and field‐activated conduction, enabling the design of oxide‐based electronic and energy devices with thermally tunable functionality.
Beatriz Moura Gomes, Júlia Holtz, Maria Luís Pinto, Maria Helena Braga   +3 more
wiley   +1 more source

Aerobic Exercise Induces Alternative Splicing of Neurexins in Frontal Cortex

Journal of Functional Morphology and Kinesiology, 2021
Aerobic exercise (AE) is known to produce beneficial effects on brain health by improving plasticity, connectivity, and cognitive functions, but the underlying molecular mechanisms are still limited.
Elisa Innocenzi, Ida Cariati, Emanuela De Domenico, Erika Tiberi, Giovanna D’Arcangelo, Veronica Verdile, Maria Paola Paronetto, Virginia Tancredi, Marco Barchi, Pellegrino Rossi, Claudio Sette, Paola Grimaldi   +11 more
doaj   +1 more source