Results 211 to 220 of about 173,508 (267)
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Metaplasticity: the plasticity of synaptic plasticity
Trends in Neurosciences, 1996In this paper, we review experimental evidence for a novel form of persistent synaptic plasticity we call metaplasticity. Metaplasticity is induced by synaptic or cellular activity, but it is not necessarily expressed as a change in the efficacy of normal synaptic transmission.
W C, Abraham, M F, Bear
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Synaptic plasticity in the subiculum
Progress in Neurobiology, 2009The subiculum is the principal target of CA1 pyramidal cells. It functions as a mediator of hippocampal-cortical interaction and has been proposed to play an important role in the encoding and retrieval of long-term memory. The cellular mechanisms of memory formation are thought to include long-term potentiation (LTP) and depression (LTD) of synaptic ...
Joachim, Behr +3 more
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Synaptic plasticity and addiction
Nature Reviews Neuroscience, 2007Addiction is caused, in part, by powerful and long-lasting memories of the drug experience. Relapse caused by exposure to cues associated with the drug experience is a major clinical problem that contributes to the persistence of addiction. Here we present the accumulated evidence that drugs of abuse can hijack synaptic plasticity mechanisms in key ...
Julie A, Kauer, Robert C, Malenka
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NEUROTROPHINS AND SYNAPTIC PLASTICITY
Annual Review of Neuroscience, 1999▪ Abstract  Despite considerable evidence that neuronal activity influences the organization and function of circuits in the developing and adult brain, the molecular signals that translate activity into structural and functional changes in connections remain largely obscure.
A K, McAllister, L C, Katz, D C, Lo
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Lithium and synaptic plasticity
Bipolar Disorders, 1999Lithium, a small cation, has been used in the treatment of bipolar disorders since its introduction in the 1950s by John Cade. Extensive research on the mechanism of action of lithium has revealed several possible targets. For some time, the most widely accepted action of lithium was its inhibitory effect on the synthesis of inositol, resulting in ...
P C, Salinas, A C, Hall
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