Results 281 to 290 of about 1,092,184 (348)

Experience-dependent critical period for synaptic plasticity in the rat olfactory amygdala. [PDF]

Front Synaptic Neurosci
Aburto-Ponce B, Fernández-Aburto P, Mpodozis J, Bacigalupo J, Sanhueza M.   +4 more
europepmc   +1 more source

Adaptive Network Stabilization Despite Profound Structural Reorganization in Human Organotypic Cultures

Advanced Science, EarlyView.
Adult human organotypic cortical slices undergo marked neuronal loss, laminar disruption, and glial activation, yet their network activity progressively stabilizes after a variable period. Electrophysiology, longitudinal calcium imaging, and quantitative histology show that structurally remodeled human circuits show adaptive capacity resulting in ...
Estilla Zsófia Tóth, Rebeka Stelcz, Réka Bod, Ábel Petik, Eszter Juhász, Kinga Tóth, Liza Szalai, Nour Essam, Fanni Somogyi, Beatrix Kovács, Amirmahdi Mojtahedzadeh, Attila György Bagó, Loránd Erőss, Péter Orbay, Johanna Petra Szabó, Dániel Fabó, Boglárka Hajnal, Bence Rácz, Daniel Hillier, István Ulbert, Lucia Wittner   +20 more
wiley   +1 more source

A Bio‐Inspired Visual Sensor With UV‐to‐NIR Fusion for Enhanced Recognition in Autonomous Driving Systems

Advanced Science, EarlyView.
Inspired by the sophisticated multilayer retinal architecture found in Pacific salmon eyes, a novel van der Waals heterojunction sensor based on NbNiTe5/BP is designed. Upon illumination at distinct wavelengths of 365 and 820 nm, the device exhibits distinctive bipolar photocurrent responses with opposite polarities. This unique optoelectronic behavior
Tianle Zeng, Zishen Zhao, Keqin Tang, Yawen Luo, Junxin Yan, Kun Ye, Jinlu Liu, Zhuo Dong, Zhipeng Yu, Weiming Lv, Ruicheng Li, Yenasheng Li, Lixuan Liu, Tianyu Xue, Chun Zhao, Yan Zhou, Kai Zhang, Zhongming Zeng, Zhongyuan Liu   +18 more
wiley   +1 more source

Hederagenin Attenuates Morphine Addiction via GABAA1‐Mediated Modulation of Ca2+–CaMK–CREB Signaling in Ventral Tegmental Dopaminergic Neurons

Advanced Science, EarlyView.
Hederagenin is identified as a GABAA1‐targeting natural compound that suppresses morphine‐associated reward by restraining Ca2+–CaMK–cAMP–CREB signaling in ventral tegmental dopaminergic neurons. RVG29‐modified liposomal delivery further enhances brain accumulation and behavioral efficacy, providing a mechanistically defined strategy for natural ...
Hongyang Jiang, Ziting Zhou, Nannan Xue, Jiasi Deng, Yuanyuan Zhou, Xinying Lv, Yuxuan Wang, Yi Zhang, Haotian Pan, Geyan Xu, Yinkun Tao, Mengran Li, Xin Cui, Hongyue Ma, Qian Wang, Zhigang Lu   +15 more
wiley   +1 more source

Temporal‐Targeted Accelerated 40 Hz tACS Enhances Cognitive Function and Network Integration in Alzheimer's Disease: A Randomized Clinical Trial

Advanced Science, EarlyView.
Bilateral temporal accelerated 40‐Hz tACS improves cognitive function in patients with Alzheimer's disease. Resting‐state fNIRS identifies treatment‐related increases in frontotemporoparietal functional connectivity, which are associated with cognitive improvement. ABSTRACT The temporal lobes are key hubs for memory and cognition.
Rong Guo, Xingxing Li, Chenjun Zou, Chao Zheng, Xiaohong Wu, Xuechao Lu, Jiaying Yan, Junfang Zhang, Xiaoyan Luo, Shiwei Ye, Dongsheng Zhou   +10 more
wiley   +1 more source

Astrocytes Coordinate Neurovascular Coupling During Prolonged Sensory Demand via AQP4/TRPA1/BEST1/D‐Serine Signaling

Advanced Science, EarlyView.
Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han, Minwoo Wendy Jang, Taeyoung Park, Ki Jung Kim, Victor James Drew, Sunpil Kim, Tai Young Kim, Mingu Gordon Park, Myeongju Kim, Seung Won Chung, Minah Suh, C. Justin Lee   +11 more
wiley   +1 more source

Genetic inactivation of Translin/Trax RNase disrupts miRNAs, hippocampal synaptic plasticity, and memory. [PDF]

iScience
Shetty MS, Kasuya J, Fu X, Lauffer MC, Tadinada SM, Chowdhury TC, Peterson Z, Carter KD, Baraban JM, Abel T.   +9 more
europepmc   +1 more source

Local translational repression and retention of SynGAP1 during synaptic plasticity

Livingstone RW, Donlin-Asp PG.
europepmc   +1 more source