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Synaptic plasticity in the subiculum
Progress in Neurobiology, 2009The subiculum is the principal target of CA1 pyramidal cells. It functions as a mediator of hippocampal-cortical interaction and has been proposed to play an important role in the encoding and retrieval of long-term memory. The cellular mechanisms of memory formation are thought to include long-term potentiation (LTP) and depression (LTD) of synaptic ...
Joachim, Behr +3 more
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NEUROTROPHINS AND SYNAPTIC PLASTICITY
Annual Review of Neuroscience, 1999▪ Abstract Despite considerable evidence that neuronal activity influences the organization and function of circuits in the developing and adult brain, the molecular signals that translate activity into structural and functional changes in connections remain largely obscure.
A K, McAllister, L C, Katz, D C, Lo
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Lithium and synaptic plasticity
Bipolar Disorders, 1999Lithium, a small cation, has been used in the treatment of bipolar disorders since its introduction in the 1950s by John Cade. Extensive research on the mechanism of action of lithium has revealed several possible targets. For some time, the most widely accepted action of lithium was its inhibitory effect on the synthesis of inositol, resulting in ...
P C, Salinas, A C, Hall
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Naturwissenschaften, 1979
Synaptic plasticity is manifested by long-lasting changes in synaptic potency. Increased potency is of special importance in relation to the neural basis of memory. Even mild repetitive stimulation evokes large and prolonged potentiations of hippocampal synapses, as is revealed by electrical recording either in vivo or in vitro.
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Synaptic plasticity is manifested by long-lasting changes in synaptic potency. Increased potency is of special importance in relation to the neural basis of memory. Even mild repetitive stimulation evokes large and prolonged potentiations of hippocampal synapses, as is revealed by electrical recording either in vivo or in vitro.
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Cell Calcium, 1998
A major effort in neuroscience is directed towards understanding the roles of Ca2+ signalling in the induction of synaptic plasticity. Here, we summarize the evidence concerning Ca2+ signalling, paying particular attention to CA1 excitatory synapses, and its relationship to the induction of long-term potentiation and long-term depression.
R, Chittajallu +2 more
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A major effort in neuroscience is directed towards understanding the roles of Ca2+ signalling in the induction of synaptic plasticity. Here, we summarize the evidence concerning Ca2+ signalling, paying particular attention to CA1 excitatory synapses, and its relationship to the induction of long-term potentiation and long-term depression.
R, Chittajallu +2 more
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Photoelectric Synaptic Plasticity Realized by 2D Perovskite
Advanced Functional Materials, 2019Recently, several light‐stimulated artificial synaptic devices have been proposed to mimic photonic synaptic plasticity for neuromorphic computing. Here, the photoelectric synaptic plasticity based on 2D lead‐free perovskite ((PEA)2SnI4) is demonstrated.
Yi-Lin Sun +8 more
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Synaptic Plasticity and Dysconnection in Schizophrenia
Biological Psychiatry, 2006Current pathophysiological theories of schizophrenia highlight the role of altered brain connectivity. This dysconnectivity could manifest 1) anatomically, through structural changes of association fibers at the cellular level, and/or 2) functionally, through aberrant control of synaptic plasticity at the synaptic level.
Stephan, K E, Baldeweg, T, Friston, K J
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Neurotrophins and Synaptic Plasticity
2013It has been suggested that long-term modifications of synaptic transmission constitute the foundation of the processes by which information is stored in the central nervous system. A group of proteins called neurotrophins are considered powerful molecular mediators in central synaptic plasticity. Among these, brain-derived neurotrophic factor (BDNF) as
Andrea, Gómez-Palacio-Schjetnan +1 more
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Neurology, 1995
Synaptic Plasticity: Molecular, Cellular, and Functional Aspects edited by MICHEL BAUDRY, RICHARD F. THOMPSON, and JOEL L. DAVIS, 263 pp., ill., Cambridge, MA, The MIT Press, 1993. $50.00 Plasticity may be defined as changes in the strength of specific synaptic connections in response to a stimulus, usually partial deafferentation or activity ...
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Synaptic Plasticity: Molecular, Cellular, and Functional Aspects edited by MICHEL BAUDRY, RICHARD F. THOMPSON, and JOEL L. DAVIS, 263 pp., ill., Cambridge, MA, The MIT Press, 1993. $50.00 Plasticity may be defined as changes in the strength of specific synaptic connections in response to a stimulus, usually partial deafferentation or activity ...
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