Results 231 to 240 of about 304,453 (323)

The DMHGABA Neurons Play a Crucial Role in The Regulation of Cold‐Induced White Adipose Browning through DMH to LPO Projection

Advanced Science, EarlyView.
GABAergic neurons in the dorsomedial hypothalamus (DMHGABA neurons) act as a key neuronal population controlling cold exposure‐induced white adipose tissue browning. DMHGABA neurons regulate the browning through DMH to the lateral preoptic area (LPO) projection.
Zhijie Su, Yujia Hou, Bingwei Wang, Qian Zhou, Wen Yang, Bingbing Guo, Chenyu Zhang, Miao Zhao, Xiaoning Yang, Jiarui Liu, Xiangyang Xie, Lihua Qin, Weiguang Zhang, Wei L. Shen, Ruimao Zheng   +14 more
wiley   +1 more source

Neuroendocrine Control of Synaptic Transmission by PHAC-1 in <i>C. elegans</i>. [PDF]

J Neurosci
Stratigi A, Soler-García M, Krout M, Shukla S, De Bono M, Richmond JE, Laurent P.   +6 more
europepmc   +1 more source

GABAergic mechanisms of excitation and hypersynchrony in adult rat hippocampus [PDF]

, 2003
Uusisaari, Marylka
core  

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Impaired synaptic transmission and long-term potentiation in severe combined immunodeficient (SCID) mice. [PDF]

Neuroreport
Lupacchini L, Mollinari C, Tancredi V, Garaci E, Merlo D.   +4 more
europepmc   +1 more source

LncRNA THUMPD3‐AS1 Regulates Behavioral and Synaptic Structural Abnormalities in Schizophrenia via miR‐485‐5p and ARHGAP8

Advanced Science, EarlyView.
Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong, Lingxi Chen, Xin Guo, Anna Jiang, Yayi He, Chunxia Yan, Liang Ma, Jiayang Gao, Jinyu Zhang, Bao Zhang   +9 more
wiley   +1 more source

Basic Science and Pathogenesis. [PDF]

Alzheimers Dement
Dougalis A, Abushik P, Pelkonen A, Giudice L, Gomez-Budia M, Novosolova N, Välimäki NN, Rezaie M, Nurkhametova D, Giniatullina R, Shakirzyanova A, Mali A, de Kock CP, Mertens EJ, Mansvelder HD, Stevens B, Macosko E, Hiltunen M, Rauramaa T, Leinonen V, Malm T.   +20 more
europepmc   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

GABA_AR-PPT1 palmitoylation homeostasis controls synaptic transmission and circuitry oscillation. [PDF]

Transl Psychiatry
Tong J, Gao J, Qi Y, Gao Z, Wang Q, Liu Y, Yuan T, Ren M, Yang G, Li Z, Li J, Sun H, Zhao X, Leung YY, Mu Y, Xu J, Lu C, Peng S, Ge L.   +18 more
europepmc   +1 more source