Results 91 to 100 of about 6,519,238 (204)

EP300‐interacting inhibitor of differentiation 3 is required for spermatogenesis in mice

Andrology, Volume 13, Issue 7, Page 1901-1912, October 2025.
Abstract Background Mammalian spermatogenesis is a highly complex process of cell proliferation, meiosis, and differentiation. A series of genes are expressed in an orderly and precise manner to ensure spermatogenesis, with chromatin undergoing intricate changes throughout.
Ping Zhang, Longsheng Zhang, Li Yu, Xinli Zhou, Xu Chen, Yuchuan Zhou, Ningling Wang, Hui Zhu   +7 more
wiley   +1 more source

Errors in chromosome segregation during oogenesis and early embryogenesis [PDF]

, 2010
Errors in chromosome segregation occurring during human oogenesis and early embryogenesis are very common. Meiotic chromosome development during oogenesis is subdivided into three distinct phases.
A Dyban, A Kuliev, A Kuliev, A Mantzouratou, A Pujol, AL Barlow, C Gutierrez-Mateo, C Gutierrez-Mateo, C Staessen, C Tease, C Tease, C Tease, C Yuncken, CM Conn, CM Conn, D Wells, D Wells, E Bendsen, E Fragouli, E Fragouli, E Fragouli, E Fragouli, E Iwarsson, EY Cheng, F Pellestor, F Pellestor, G Sher, HE Hall, J Cohen, J Cozzi, JD Delhanty, JD Delhanty, JD Delhanty, JD Delhanty, KT Jones, L Gianaroli, L Gras, L Voullaire, L Voullaire, L Wilton, M Hultén, M Sandalinas, M Simopoulou, MA Hultén, ML Lenzi, NV Kovaleva, P Platteau, PA Almeida, PA Hunt, R Angell, R Mahmood, S Cupisti, S Evsikov, S Mastenbroek, S Munné, S Munné, S Munné, S Munné, S Munné, S Munné, S Munné, S Munné, T Anahory, T Hassold, TR Oliver, Y Verlinsky   +65 more
core   +1 more source

Comparative Genomics of Sex‐Determination‐Related Genes Reveals Shared Evolutionary Patterns Between Bivalves and Mammals, but Not Fruit Flies

Molecular Ecology, Volume 34, Issue 20, October 2025.
ABSTRACT The molecular basis of sex determination (SD), while being extensively studied in model organisms, remains poorly understood in many animal groups. Bivalves, a diverse class of molluscs with a variety of reproductive modes, represent an ideal yet challenging clade for investigating SD and the evolution of sexual systems.
Filippo Nicolini, Sergey V Nuzhdin, Fabrizio Ghiselli, Andrea Luchetti, Liliana Milani   +4 more
wiley   +1 more source

Interplay between synaptonemal complex, homologous recombination, and centromeres during mammalian meiosis. [PDF]

PLoS Genetics, 2012
The intimate synapsis of homologous chromosome pairs (homologs) by synaptonemal complexes (SCs) is an essential feature of meiosis. In many organisms, synapsis and homologous recombination are interdependent: recombination promotes SC formation and SCs ...
Huanyu Qiao, Jefferson K Chen, April Reynolds, Christer Höög, Michael Paddy, Neil Hunter   +5 more
doaj   +1 more source

The synaptonemal complex has liquid crystalline properties and spatially regulates meiotic recombination factors

eLife, 2017
The synaptonemal complex (SC) is a polymer that spans ~100 nm between paired homologous chromosomes during meiosis. Its striated, periodic appearance in electron micrographs led to the idea that transverse filaments within this structure ‘crosslink’ the ...
O. Rog, S. Köhler, A. Dernburg
semanticscholar   +1 more source

Manipulating Unisexual–Sexual Reproduction Transition to Engineer Genome‐Reconstructed Polyploids

Advanced Science, Volume 12, Issue 33, September 4, 2025.
This study developed an efficient approach to generate genome‐reconstructed polyploids involving unisexual gynogenetic Carassius gibelio, sexual C. auratus, and sexual C. cuvieri. The selected superior clone inherited gynogenesis ability of C. gibelio and herpesvirus resistance of wild C.
Meng Lu, Qin‐Can Zhang, Zi‐Yu Zhu, Yang Wang, Zhong‐Wei Wang, Xi‐Yin Li, Zhi Li, Xiao‐Juan Zhang, Li Zhou, Jian‐Fang Gui   +9 more
wiley   +1 more source

TRIP13PCH-2 promotes Mad2 localization to unattached kinetochores in the spindle checkpoint response. [PDF]

, 2015
The spindle checkpoint acts during cell division to prevent aneuploidy, a hallmark of cancer. During checkpoint activation, Mad1 recruits Mad2 to kinetochores to generate a signal that delays anaphase onset.
Bhalla, Needhi, Chen, Pin-Hsi, Hwang, Tom, Nelson, Christian R   +3 more
core   +1 more source

The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility.

PLoS Genetics, 2019
The ubiquitin proteasome system regulates meiotic recombination in yeast through its association with the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I.
Laura Gómez-H, Natalia Felipe-Medina, Yazmine B Condezo, Rodrigo Garcia-Valiente, Isabel Ramos, José Angel Suja, José Luis Barbero, Ignasi Roig, Manuel Sánchez-Martín, Dirk G de Rooij, Elena Llano, Alberto M Pendas   +11 more
doaj   +1 more source

OsRAD17 Is Required for Meiotic Double-Strand Break Repair and Plays a Redundant Role With OsZIP4 in Synaptonemal Complex Assembly

Frontiers in Plant Science, 2018
The repair of SPO11-dependent double-strand breaks (DSBs) by homologous recombination (HR) ensures the correct segregation of homologous chromosomes. In yeast and human, RAD17 is involved in DNA damage checkpoint control and DSB repair.
Qing Hu, Qing Hu, Chao Zhang, Chao Zhang, Zhihui Xue, Lijun Ma, Wei Liu, Yi Shen, Bojun Ma, Zhukuan Cheng, Zhukuan Cheng   +10 more
doaj   +1 more source

Mixing and Matching Chromosomes during Female Meiosis

Cells, 2020
Meiosis is a key event in the manufacturing of an oocyte. During this process, the oocyte creates a set of unique chromosomes by recombining paternal and maternal copies of homologous chromosomes, and by eliminating one set of chromosomes to become ...
Thomas Rubin, Nicolas Macaisne, Jean-René Huynh   +2 more
doaj   +1 more source