Chromosomal rearrangements can lead to the formation of new stable karyotypes, nevertheless changing the architectonics of the nucleus. The differences in locations might promote Robertsonian (Rb) translocations and encourage meiotic drive in favour of ...
V. G. Tambovtseva +5 more
doaj +1 more source
TRIP13PCH-2 promotes Mad2 localization to unattached kinetochores in the spindle checkpoint response. [PDF]
The spindle checkpoint acts during cell division to prevent aneuploidy, a hallmark of cancer. During checkpoint activation, Mad1 recruits Mad2 to kinetochores to generate a signal that delays anaphase onset.
Bhalla, Needhi +3 more
core +1 more source
This article presents a detailed ultrastructural cell atlas of Plasmodium ookinete development using advanced volume electron microscopy (v) techniques. It defines seven distinct developmental stages, revealing complex organelle interactions and offering new insights into parasite differentiation.
Nedal Darif +12 more
wiley +1 more source
Telomeres cluster de novo before the initiation of synapsis: a three-dimensional spatial analysis of telomere positions before and during meiotic prophase. [PDF]
We have analyzed the progressive changes in the spatial distribution of telomeres during meiosis using three-dimensional, high resolution fluorescence microscopy.
Agard, DA +4 more
core
Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids
To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun +9 more
wiley +1 more source
Sequential Loading of Cohesin Subunits during the First Meiotic Prophase of Grasshoppers [PDF]
A previous version of this article appeared as an Early Online Release on January 2, 2007 (doi:10.1371/journal.pgen.0030028.eor).The cohesin complexes play a key role in chromosome segregation during both mitosis and meiosis.
Valdeolmillos, Ana M. +10 more
core +1 more source
FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis [PDF]
Nobuhiro Tanno +8 more
openalex +1 more source
New method for visualization of C-heterochromatin in synaptonemal complex spreads
DAPI staining of the metaphase chromosomes pretreated with barium hydroxide generates a C-like banding pattern. In this work a protocol for visualizing similar pattern at the synaptonemal complex (SC) spreads after immunostaining is suggested.
Artem Lisachov
doaj +1 more source
Intercellular Migration of Centrioles in the Germarium of \u3cem\u3eDrosophila melanogaster\u3c/em\u3e. An Electron Microscopic Study [PDF]
A cluster of centrioles has been found in the early Drosophila oocyte. Since the oocyte is connected to 15 nurse cells by a system of intercellular bridges or ring canals, the possibility that the cluster of centrioles arose in the germarium from an ...
Mahowald, Anthony P. +1 more
core +1 more source
High density of REC8 constrains sister chromatid axes and prevents illegitimate synaptonemal complex formation [PDF]
During meiosis, cohesin complexes mediate sister chromatid cohesion (SCC), synaptonemal complex (SC) assembly and synapsis. Here, using super-resolution microscopy, we imaged sister chromatid axes in mouse meiocytes that have normal ...
Abrahan Hernández‐Hernández +8 more
core +1 more source

