Results 121 to 130 of about 6,967 (166)

Is the Synaptonemal Complex a Disjunction Machine?

Journal of Heredity, 1995
The chiasma has been recognized as a major feature of meiosis both visually and functionally for > 85 years. But its functional basis remains poorly understood. In interaction with the spindle, it generally mediates the ultimate distribution of homologues to opposite poles at meiosis I to yield correct disjunction.
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Regulating the construction and demolition of the synaptonemal complex

Nature Structural & Molecular Biology, 2016
The synaptonemal complex (SC) is a meiosis-specific scaffold that links homologous chromosomes from end to end during meiotic prophase and is required for the formation of meiotic crossovers. Assembly of SC components is regulated by a combination of associated nonstructural proteins and post-translational modifications, such as SUMOylation, which ...
Cori K, Cahoon, R Scott, Hawley
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THE GENETICS AND MOLECULAR BIOLOGY OF THE SYNAPTONEMAL COMPLEX

Annual Review of Cell and Developmental Biology, 2004
▪ Abstract  The synaptonemal complex (SC) is a protein lattice that resembles railroad tracks and connects paired homologous chromosomes in most meiotic systems. The two side rails of the SC, known as lateral elements (LEs), are connected by proteins known as transverse filaments.
Page, Scott, Hawley, R
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The synaptonemal complex and the achiasmatic condition

Journal of Cell Science, 1973
ABSTRACT The onion species AUium amplectans includes both a triploid and a tetraploid variety. By light microscopy both varieties appear to have normal synapsis during pachytene of meiosis. However, the triploid does not form chiasmata and exhibits almost total asynapsis following pachytene.
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Changes of the synaptonemal complex at the end of pachytene

Human Genetics, 1973
Observations on the changes of the synaptonemal complex at the end of pachytene and in diplotene are reported. The synaptonemal complex disintegrates in diplotene by progressive disjoining of the lateral arms. The structures of the pairing space disappear.
E, Schleiermacher, W, Schmidt
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Searching for synaptonemal complex proteins and their genes

Developmental Genetics, 1992
AbstractAs an alternative to the production and use of monoclonal antisynaptonemal complex (SC) antibodies to isolate SC genes, we have explored the use of polyclonal anti‐SC antibodies to identify SC genes from a cDNA expression library. The method proved relatively simple, reliable, and fast and has yielded two SC genes.
P B, Moens, B, Spyropoulos, M, Dobson, A, Karaiskakis, R E, Pearlman   +4 more
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Synaptonemal complexes: structure and function

Current Opinion in Cell Biology, 1996
Synaptonemal complexes (SCs) are zipper-like structures which are assembled between homologous chromosomes during the prophase of the first meiotic division. Their assembly and disassembly correlate with the successive chromatin rearrangements of meiotic prophase, namely the condensation, pairing, recombination and disjunction of homologous chromosomes.
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Scanning electron microscopy of synaptonemal complexes

Chromosome Research, 1993
The novel application of scanning electron microscopy to study whole-mount surface-spread synaptonemal complex complements of rye (Secale cereale) and rat (Rattus norvegicus) is described. Scanning electron microscopy is able to resolve the third dimension in such preparations and improve the tracing of the continuity of lateral elements without losing
A L, Barlow, G, Jenkins, I, ap Gwynn
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Synaptonemal complexes in insects

International Journal of Insect Morphology and Embryology, 1996
Abstract The synaptonemal complex (SC) is the key nuclear element formed in meiotic prophase I to join 2 homologous chromosomes at the pachytene bivalent. It is a highly conserved structure that is universally present in eukaryotes. The SC is presented as a tripartite protein structure, which consists of 2 lateral elements and a central region.
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Synaptonemal complexes in a tetraploid mouse spermatocyte

Experimental Cell Research, 1977
Summary Quadrivalents, represented by unique synaptonemal complex configurations, together with normal bivalents are observed for the first time in a mammalian tetraploid pachytene spermatocyte prepared by microspreading. The chromosomal axes (lateral elements) clearly demonstrate the switching of partners in the quadrivalents as predicted from ...
A J, Solari, M J, Moses
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