Results 51 to 60 of about 343,063 (299)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

A novel conceptual design method for aviation PMSG based on thermal modeling

International Journal for Simulation and Multidisciplinary Design Optimization
A multi-disciplinary optimization design method for permanent magnet synchronous generators based on thermal modeling is proposed in this paper. The complex coupling among the thermal, electromagnetic, and mechanical systems and the difficulties in ...
Wang He, Ai Fengming, He Linke, Zhou Zhongzheng, Wang Yangang   +4 more
doaj   +1 more source

A nonlinear adaptive excitation controller design for two‐axis models of synchronous generators in multimachine power systems to augment the transient stability during severe faults

IET Generation, Transmission & Distribution, 2022
This paper presents an excitation controller design process for multimachine power systems with synchronous generators using an adaptive backstepping approach to ensure robust performance against parametric uncertainties as well as to improve the ...
Tushar Kanti Roy, Md Apel Mahmud
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

A Comparative Study of Modular Axial Flux Podded Generators for Marine Current Turbines [PDF]

, 2014
This research note deals with performance comparison of axial flux modular podded generators for marine current turbines (MCTs). Due to the submarine environment, maintenance operations are very hard, very costly, and strongly depending on sea conditions.
CHARPENTIER, Jean-Frederic, SCUILLER, Franck, BENBOUZID, Mohamed, Charpentier, Jean Frédéric, DJEBARRI, Sofiane   +4 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Contribuição à determinação das reatâncias não saturadas de máquinas síncronas de polos lisos laminados [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2013.Apresenta-se nessa dissertação um estudo das reatâncias não saturadas de máquinas síncronas de ...
Mendonça, Aline Jorge
core  

Pre Synchronization Control Strategy of Virtual Synchronous Generator (VSG) in Micro-Grid

IEEE Access, 2023
The constant increase of energy demand and the widespread adoption of renewable energy sources have led to the significant interest in micro-grids, which are small-scale power systems that utilize distributed energy resources.
Jianfeng Wang, Nurulazlina Ramli, Noor Hafizah Abdul Aziz   +2 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source