Results 221 to 230 of about 218,510 (301)

Respiratory‐Limbic Coupling via a Thalamic Circuit Alleviates Anxiety

Advanced Science, EarlyView.
This study delineates a conserved preBötCGlu→PVT→CeA circuit that gates anxiety and respiration. Activation of this circuit is anxiolytic and respiratory‐stabilizing, while its inhibition has the opposite effect. Mechanistically, PVT exerts its anxiolytic action via a disinhibitory microcircuit: its inputs preferentially target CeL GABAergic neurons ...
Shangyu Bi, Xiaoyi Wang, Huichun Luo, Ziteng Yue, Tianjiao Deng, Yuhang Liu, Xinxin Chen, Jianxu Zhao, Luo Shi, Ning Ma, Lingyan Mao, Jing Ding, Jiwen Xu, Ti‐Fei Yuan, Sheng Wang, Fang Yuan   +15 more
wiley   +1 more source

Multifocal Breast Cancer With Discordant Molecular Profiles in a Patient With NF1 and MUTYH Germline Variants: A Case Report. [PDF]

Cureus
Su L, Lu AY, Narasimhamurthy M.
europepmc   +1 more source

Coordination of Cyanobacterial Nitrate Assimilation and Photosynthesis by a Novel PsbO‐Interacting Protein PirN

Advanced Science, EarlyView.
PirN was identified as a previously uncharacterized PsbO‐interacting protein specifically induced in nitrate‐grown cyanobacteria. Loss of PirN leads to coordinated downregulation of PsbO and the nitrate reductase NarB, causing decreased PSII activity and impaired growth under nitrate conditions. Complementation with either PsbO or NarB largely restores
Chengcheng Huang, Zhen Xiao, Haitao Ge, Gaojie Wang, Jinghui Dong, Yan Wang, Hang Yang, Xing Wang, Hui Gao, Zhongshu Wang, Huanling Yang, Yuanya Zhang, Xiahe Huang, Wu Xu, Weimin Ma, Wenqiang Yang, Yingchun Wang   +16 more
wiley   +1 more source

Second lesions located within the same belt-like region along the stomach's short axis as primary lesions: Boundary equal lesion trends. [PDF]

Endosc Int Open
Iida T, Kimoto Y, Yamabe E, Kanamori M, Banjoya S, Kimura T, Furuta K, Nagae S, Yamazaki H, Takeuchi N, Takayanagi S, Konishi T, Kano Y, Ono K, Negishi R, Minato Y, Chiba H, Ohata K.   +17 more
europepmc   +1 more source

Cognitive Trajectories from Preclinical Alzheimer's Disease to Dementia

Advanced Science, EarlyView.
A continuous, multi‐domain characterization of cognitive decline across the Alzheimer's disease spectrum identifies when individual cognitive measures become abnormal. Episodic memory declines first, followed by executive function, language, processing speed, and visuospatial abilities, supporting improved clinical interpretation and optimized endpoint
Fredrik Öhman, Lars Lau Raket, Michael Schöll, for the Alzheimer's Disease Neuroimaging Initiative†   +3 more
wiley   +1 more source

Triple Synchronous Primary Malignant Tumors of the Liver, Kidney, and Lung in a Male Patient: Case Report and Systematic Review. [PDF]

Diagnostics (Basel)
Oprița AV, Achim E, Nițipir C, Boleac N, Pilatec AN, Grama FA.   +5 more
europepmc   +1 more source

Lewis Pair‐Engineered CuMnOx as Cold‐Adapted Multinanozyme for Cooperative Hydrolytic and Oxidative Degradation of Raw Corn Stalk

Advanced Science, EarlyView.
A Lewis pair site design strategy was established to construct Cu‐doped Mn‐based amorphous nanozymes, where Mn and oxygen vacancies generate cooperative acid‐base pairs. The resulting multinanozyme integrates glycosidase‐, oxidase‐, and cold‐adapted enzyme‐mimicking activities, enabling cooperative depolymerization of cellulose and hemicellulose ...
Huile Liu, Ziyi Di, Qing Tian, Yue Zhou, Rong Yang, Zhiyi Bai, Haoyu Wang, Yao Chen, Lianbing Zhang   +8 more
wiley   +1 more source

A Deep Learning Algorithm for Liver Metastasis Detection at Contrast-enhanced Abdominal CT in Patients with Colorectal Cancer: A Comparative Study with Radiologists. [PDF]

Radiol Imaging Cancer
Sartoris R, Paisant A, Bône A, Nicolas F, Malakzadeh S, Matteini F, Dioguardi Burgio M, Vilgrain V, Ronot M, Aubé C.   +9 more
europepmc   +1 more source

WUSCHEL Transcription Factor: From Stem Cell Maintenance to Crop Improvement

Advanced Science, EarlyView.
This review synthesizes emerging insights into WUSCHEL (WUS) as a central regulator of plant stem cell fate beyond Arabidopsis, highlighting its roles in regeneration, somatic embryogenesis (SE), and stress adaptation across crops. It explores how WUS‐centered regulatory networks, genome editing, and AI‐guided strategies can be leveraged for precise ...
Zishan Ahmad, Muthusamy Ramakrishnan, Rajeev K. Varshney, Anwar Shahzad, Shamsur Rehman, Bijaya Pant, Qiang Wei   +6 more
wiley   +1 more source

A scoring system for screening of patients with synchronous bone metastasis in lung cancer. [PDF]

Medicine (Baltimore)
Zhao W, Lin Y, Wu H, Wang J, Chekhonin VP, Kaprin AD, Musaev ER, Zhang J, Guo X, Zhang C.   +9 more
europepmc   +1 more source