Results 91 to 100 of about 109,055 (295)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
, 2013 Presents an early embryonic divisions in Drosophila are syncytial. Nuclei undergo mitosis synchronously for the first 14 nuclear cycles, followed by cellularization (Foe and Alberts, 1983).
Silverman-Gavrila, Rosalind V.
core +2 more sources
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Processing fluency for visual synchrony perception
, 2022 Synchrony is an important aspect of social behaviour. Prior research has observed a synchrony-bonding effect, suggesting that synchronised action may be an efficient way of creating and maintaining social affiliation.
Joshua S. Bamford +1 more
core +1 more source
Broadscale spatial synchrony in a West Nile virus mosquito vector across multiple timescales
Scientific ReportsInsects often exhibit irruptive population dynamics determined by environmental conditions. We examine if populations of the Culex tarsalis mosquito, a West Nile virus (WNV) vector, fluctuate synchronously over broad spatial extents and multiple ...
Lindsay P. Campbell +4 more
doaj +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
Calculi for synchrony and asynchrony
Theoretical Computer Science, 1983 AbstractA calculus for distributed computation is studied, based upon four combinators. A central idea is an Abelian group of actions which models the interfaces between components of a distributed computing agent. Using a notion of bisimulation, congruence relations are defined over computing agents, and thence an algebraic theory is derived.
openaire +3 more sources
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Interpersonal neural synchrony across levels of interpersonal closeness and social interactivity
NeuroImageInterpersonal neural synchrony is a fundamental aspect of social interactions, offering insights into the neural mechanisms underlying human connection and developmental outcomes.
Alessandro Carollo +5 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source