Results 121 to 130 of about 94,006 (299)

Magnetic Thermal Ablation Combined with Temporally Coordinated CpG Immunotherapy Promotes cDC1‐Dependent Immune Priming in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Novel PLA@Fe3O4 magnetic microspheres were developed for transarterial magnetic hyperthermia ablation (MTA) of hepatocellular carcinoma. While destroying local tumors and inducing immunogenic cell death (ICD), MTA combined with early CpG adjuvant administration significantly promotes cDC1‐dependent immune priming. This synergistic mechanism effectively
Jiakun Yang, Nailin Yang, Shuangshuang Ji, Siping Meng, Di Wang, Wenjun Liang, Xuming Bai, Yong Jin, Xingwei Sun   +8 more
wiley   +1 more source

Appropriate Evaluation of Syncope

, 2020
The purpose of this article is to determine the best syncope risk stratification score currently available as well as review appropriate syncope diagnosis and management.
Bilby, Kristen
core   +1 more source

Predictors of Mortality, Rehospitalization for Syncope, and Cardiac Syncope in 352 Consecutive Elderly Patients With Syncope

, 2013
OBJECTIVES: To investigate the etiologies of syncope and predictors of all-cause mortality, rehospitalization, and cardiac syncope in consecutive elderly patients presenting with syncope to our emergency department.
Aronow, Wilbert S, Palaniswamy, Chandrasekar, Peterson, Stephen J, Doshi, Jay V, Khera, Sahil, Balasubramaniyam, Nivas, Ahn, Chul, Sule, Sachin, Adapa, Sreedhar, Nabors, Christopher   +9 more
core   +1 more source

CRISPR‐Scan: Cas13a Mismatch Tolerance Enabled Ultra‐Multiplexed Detection of Same‐Site Indels in Acute Myeloid Leukemia

Advanced Science, EarlyView.
Accurately detecting diverse same‐locus insertions or deletions (indels) remains challenging. This study reveals the mismatch‐tolerance profile of LwaCas13a and establishes CRISPR‐Scan, which uses a single crRNA to detect multiple same‐locus indels. The one‐pot assay detects nucleophosmin 1 (NPM1) mutant allele frequencies down to 0.01%, agrees with ...
Linlin Bai, Bei Wang, Mingmin Shi, Dianwei Liu, Huimin Ji, Ting Wang, Ziwei Wang, Kaiming Guo, Xinyang Dou, Chunyan Qian, Fang Zhang, Yongming Wang, Hongju Mao, Rui Wang   +13 more
wiley   +1 more source

Syncope risk stratification in the ED

, 2014
Syncope may be the final common presentation of a number of clinical conditions spanning benign (i.e. neurally-mediated syncope) to life-threatening diseases (i.e. cardiac syncope). Hospitalization rate after a syncopal episode is high. An effective risk
E. Brunetta, F. Dipaola, Antonio Roberto Zamunér, Eleonora Tobaldini, G. Costantino, Enrico Brunetta, C. Capitanio, Chiara Capitanio, Raffaello Furlan, Franca Barbic, E. Tobaldini, A. Zamunér, R. Furlan, Monica Solbiati, Franca Dipaola, M. Solbiati, F. Barbic, Giorgio Costantino   +17 more
core   +1 more source

An Oral Antiviral Combination Against Severe COVID‐19 Enabled by the Synergistic Mechanisms of Action of Auranofin and Remdesivir

Advanced Science, EarlyView.
FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun, Rohan Narayan, Santhosh Kambaiah Nagaraj, Rishad Shiraz, Abinaya Kaliappan, Sumandeep Kaur, Ankur Singh, Siva Shanmugam Selvaraj, Gudepalya Renukaiah Rudramurthy, Chakenahalli Naveenkumar, Shridhar Narayanan, Radha Krishan Shandil, Shailly Tomar, Shashank Tripathi   +13 more
wiley   +1 more source

Mapping of low-voltage bridges with a high-density multipolar catheter in a child with atrioventricular nodal reentry tachycardia

HeartRhythm Case Reports, 2020
Fabrizio Drago, MD, Camilla Calvieri, MD, PhD, Greta Allegretti, BioMedEng, Massimo Stefano Silvetti, MD   +3 more
doaj   +1 more source

Spatiotemporal Computational Meta‐Imager for Broadband Dual‐Layer Optical Convolution

Advanced Science, EarlyView.
A single‐layer polarization‐multiplexed meta‐imager achieves factorized dual‐layer broadband convolution via spatiotemporal kernel decomposition. Fixed Bessel‐vortex bases and time‐sequential liquid‐crystal modulation deliver tunable signed weights and in‐situ fabrication‐error compensation. Experiments verify improved classification performance across
Mengguang Wang, Chenglong Zheng, Huaping Zang, Changwei Zhang, Huai Xia, Chang Wang, Zhenrong Zheng   +6 more
wiley   +1 more source

Synergistic Charge Scavenging in Pt/C‐Polyoxometalate Systems for Scalable Biomass Power Generation via Super‐Reduced Electrolytes

Advanced Science, EarlyView.
Synergistic charge scavenging between Pt/C and liquid polyoxometalate mediators effectively dismantles the inherent biological recalcitrance of raw biowaste. This dynamic interfacial electron transfer unlocks a multi‐electron super‐reduced state (>4 electrons). By overcoming traditional electron‐harvesting ceilings, this approach enables scalable, high‐
Hojin Lee, Hyeong‐Jin Lee, Jongseo Lee, Sang‐Soo Han, Sangjin Park, Eun Seon Cho, Hee‐Tak Kim   +6 more
wiley   +1 more source

Prevalence of pulmonary embolism in syncope patients

, 2017
Clinical questionHow often is pulmonary embolism (PE) found in patients admitted for syncope?Article chosenPrandoni P, Lensing A, Prins M, et al. Prevalence of pulmonary embolism among patients hospitalized for syncope (PESIT). N Engl J Med 2016;375:1524-
Sean Crooks, Eddy Lang
core   +1 more source