Results 101 to 110 of about 11,102 (261)

Thyroid hormone treated astrocytes induce maturation of cerebral cortical neurons through modulation of proteoglycan levels [PDF]

, 2013
Proper brain neuronal circuitry formation and synapse development is dependent on specific cues, either genetic or epigenetic, provided by the surrounding neural environment. Within the sesignals, thyroid hormones (T3 and T4) play crucial role in several
Araujo, Ana P. B., Dezonne, Romulo S., Gomes, Flavia C. A., Nones, Jader, Pavao, Mauro S. G., Porcionatto, Marimelia, Stipursky, Joice   +6 more
core   +3 more sources

Commuting by bicycle (vs. by car) is associated with improved aerobic power, microvascular function and diminished CO2 output in the atmosphere

Experimental Physiology, EarlyView.
Abstract The study investigated whether bicycle compared with car commuting, over relatively small distances, has positive effects on physiological variables, cardiometabolic fitness and CO2 output in the atmosphere. Bike Commuters (11 M, 15 F; age [median value (interquartile range)] 51.5 (38.3–56.8) years; body mass index [BMI] 22.8 (21.0–24.1) kg m ...
Caterina Ursella, Giovanni Baldassarre, Lucrezia Zuccarelli, Federica Caponnetto, Francesco Curcio, Mattia D'Alleva, Maria De Martino, Elisabetta Fontanini, Andrea Palomba, Antonio Paolo Beltrami, Federico Formenti, Bruno Grassi   +11 more
wiley   +1 more source

Association of the SNP rs2623047 in the HSPG modification enzyme SULF1 with an Australian Caucasian Breast Cancer Cohort [PDF]

, 2014
Breast cancer is the second most common cancer worldwide and the most common cancer reported in women. This malignant tumour is characterised by a number of specific features including uncontrolled cell proliferation.
Chacon Cortes, Diego Fernando, Chambers, Suzanne, Faure, Marion, Griffiths, Lyn, Haupt, Larisa, Jacinto, Jose, Okolicsanyi, Rachel, Youl, Philippa   +7 more
core   +3 more sources

Impaired nitric oxide‐dependent endothelial function in young male individuals with obesity before the onset of symptoms and complications

Experimental Physiology, EarlyView.
Abstract Endothelial dysfunction drives obesity‐related complications. Doppler ultrasound measurement of blood flow during 1‐min passive leg movements (PLM) is a valuable non‐invasive tool for assessing endothelial function and nitric oxide (NO)‐mediated vasodilation.
Lucrezia Zuccarelli, Giovanni Baldassarre, Adele Bondesan, Diana Caroli, Roberta De Micheli, Gabriella Tringali, Thomas Favaretto, Joanna Suraj‐Prazmowska, Anna Kurpinska, Joanna Majerczak, Stefan Chlopicki, Jerzy A. Zoladz, Alessandro Sartorio, Bruno Grassi   +13 more
wiley   +1 more source

GPR56 Plays Varying Roles in Endogenous Cancer Progression [PDF]

, 2009
2011 March 29GPR56, a non-classical adhesion receptor, was previously reported to suppress tumor growth and metastasis in xenograft models using human melanoma cell lines.
Barry, Marc, Begum, Shahinoor, Bronson, Roderick T., Crowley, Denise G., Hynes, Richard O., Xu, Lei, Yang, Liquan   +6 more
core   +2 more sources

Transcriptional Adaptations to Muscle Loading in a Murine Model of Achilles Tendinopathy

Journal of Orthopaedic Research, Volume 44, Issue 2, February 2026.
ABSTRACT Achilles tendinopathy limits mobility and decreases quality of life. Physical therapy (eccentric muscle loading) improves tendon function; however, the underlying mechanisms are unknown. This study investigated the effect of load magnitude and treatment duration in a mouse Achilles tendinopathy model.
Dylan C. Easley, Bruno C. Menarim, Robert W. Grange, P. Gunnar Brolinson, Vincent M. Wang, Linda A. Dahlgren   +5 more
wiley   +1 more source

A syndecan és decorin proteoglikánok kóroki szerepének modellezése májbetegségekben = Experimental models to study the significance of syndecan-1 and decorin in the development of liver diseases [PDF]

, 2007
Az elmúlt 4 évben olyan modellrendszereket dolgoztunk ki, melyekben a proteoglikánok kifejeződését megváltoztattuk. Kialakitottunk egy decorin -/- TGF béta-1 +/- kettős transzgén egértörzset, melyen a cirrhosis és a hepatokarcinogenezis eseményeit ...
Kovalszky, Ilona, Nagy, Péter, Szilák, László   +2 more
core  

Proteoglycans and neuronal migration in the cerebral cortex during development and disease [PDF]

, 2015
Chondroitin sulfate proteoglycans and heparan sulfate proteoglycans are major constituents of the extracellular matrix and the cell surface in the brain. Proteoglycans bind with many proteins including growth factors, chemokines, axon guidance molecules,
Nobuaki Maeda
core   +2 more sources

Remote Pancreatic Response to Severe Polytrauma Correlates With Clinical Outcome

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Acute pancreatic injury can result from blunt or sharp force trauma, often leading to serious complications. While direct pancreatic trauma is associated with high rates of infection, organ failure, and mortality, little is known about the pancreas as a potential secondary target and remote trauma organ and thereby as a booster of ...
Rebecca Halbgebauer, Lisa Wohlgemuth, Jonas Wrba, Sonja Braumüller, Enes Kumral, Ludmila Lupu, Clara Morgenstern, Lucas Bettac, Sebastian Wiese, Benjamin Mayer, Paolo Cinelli, Daniel Rittirsch, Hans‐Christoph Pape, Francesco Roselli, Thomas Seufferlein, Alexander Kleger, Markus Breunig, Markus Huber‐Lang   +17 more
wiley   +1 more source

Sugar Antennae for Guidance Signals: Syndecans and Glypicans Integrate Directional Cues for Navigating Neurons

The Scientific World Journal, 2006
Attractive and repulsive signals guide migrating nerve cells in all directions when the nervous system starts to form. The neurons extend thin processes, axons, that connect over wide distances with other brain cells to form a complicated neuronal ...
Christa Rhiner, Michael O. Hengartner
doaj   +1 more source