Results 31 to 40 of about 5,456,377 (265)

Severe acute respiratory syndrome-related coronavirus: The species and its viruses – a statement of the Coronavirus Study Group

bioRxiv, 2020
The present outbreak of lower respiratory tract infections, including respiratory distress syndrome, is the third spillover, in only two decades, of an animal coronavirus to humans resulting in a major epidemic. Here, the Coronavirus Study Group (CSG) of
A. Gorbalenya, S. Baker, R. Baric, R. D. de Groot, C. Drosten, Anastasia A. Gulyaeva, B. Haagmans, C. Lauber, A. M. Leontovich, B. Neuman, Dmitry Penzar, S. Perlman, L. Poon, Dmitry V. Samborskiy, I. Sidorov, I. Sola, J. Ziebuhr   +16 more
semanticscholar   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome

New England Journal of Medicine, 2018
Background Patients who have had an acute coronary syndrome are at high risk for recurrent ischemic cardiovascular events. We sought to determine whether alirocumab, a human monoclonal antibody to proprotein convertase subtilisin–kexin type 9 (PCSK9 ...
G. Schwartz, G. Steg, M. Szarek, Deepak Bhatt, Vera A. Bittner, R. Diaz, Jay M. Edelberg, Shaun G Goodman, C. Hanotin, Robert A Harrington, W. Jukema, G. Lecorps, K. Mahaffey, A. Moryusef, R. Pordy, K. Quintero, Matthew T. Roe, W. Sasiela, J. Tamby, P. Tricoci, Harvey D. White, Andreas M. Zeiher   +21 more
semanticscholar   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

The Role of Cytokines including Interleukin-6 in COVID-19 induced Pneumonia and Macrophage Activation Syndrome-Like Disease

Autoimmunity Reviews, 2020
Severe COVID-19 associated pneumonia patients may exhibit features of systemic hyper-inflammation designated under the umbrella term of macrophage activation syndrome (MAS) or cytokine storm, also known as secondary haemophagocytic lymphohistocytosis ...
D. McGonagle, K. Sharif, A. O’Regan, C. Bridgewood   +3 more
semanticscholar   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

Systematic multi-omic deconvolution of the clinical heterogeneity of Down syndrome

Nature Communications
Persons with Down syndrome, the genetic condition caused by trisomy 21, are at high risk of developing various co-occurring conditions affecting all major organ systems.
Micah G. Donovan, Srija Chillamcherla, Belinda A. Enriquez Estrada, Kayleigh R. Worek, Zenitha Sundararajan, Kyle W. Barstch, Kelly D. Sullivan, Matthew D. Galbraith, Angela L. Rachubinski, Joaquin M. Espinosa   +9 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Exploring differences in the human gut microbiome between Han Chinese and non-Chinese populations

Genome Biology
Background The human gut microbiota exhibits significant diversity across populations, influenced by factors such as geography, diet, and lifestyle, particularly between the Han Chinese and non-Chinese populations.
Jingjing Wang, Zhenmiao Zhang, Yang Chen, Xi Zhou, Jiaxin Xiang, Chao Yang, Dmitry A. Rodionov, Andrei L. Osterman, Qinwei Qiu, Yusheng Deng, Yanmin Liu, Chengrui Wang, Xiaoxiao Shang, Li Huang, Chen Sun, Jianwen Guo, Zhimin Yang, Lixiang Zhai, Zhaoxiang Bian, Aiping Lyu, Lijuan Han, Wei Jia, Xiaodong Fang, Lu Zhang   +23 more
doaj   +1 more source

Creativity Assessment in Subjects with Tourette Syndrome vs. Patients with Parkinson’s Disease: A Preliminary Study

Brain Sciences, 2017
(1) Background: Literature suggests that high levels of dopamine are associated with creative thoughts. Tourette Syndrome (TS) patients have high dopamine levels, while Parkinson’s Disease (PD) subjects have low dopamine levels.
Carlotta Zanaboni Dina, Mauro Porta, Christian Saleh, Domenico Servello   +3 more
doaj   +1 more source