Results 41 to 50 of about 4,352,139 (301)

Systematic multi-omic deconvolution of the clinical heterogeneity of Down syndrome

Nature Communications
Persons with Down syndrome, the genetic condition caused by trisomy 21, are at high risk of developing various co-occurring conditions affecting all major organ systems.
Micah G. Donovan, Srija Chillamcherla, Belinda A. Enriquez Estrada, Kayleigh R. Worek, Zenitha Sundararajan, Kyle W. Barstch, Kelly D. Sullivan, Matthew D. Galbraith, Angela L. Rachubinski, Joaquin M. Espinosa   +9 more
doaj   +1 more source

Problems lowering the study quality in traditional medicine, introspection from an example of meta-analysis of acupuncture

BMC Complementary Medicine and Therapies, 2020
Background Most randomized controlled trials (RCTs) of traditional medicine (such as traditional Chinese medicine (TCM), psychotherapy or behavioral therapy, and dietary interventions, etc.) have reported that they could not provide convincing evidence ...
Qiliang Chen, Qiong Wang, Shanshan Ding, Shunan Li, Yuanyuan Zhang, Shujiao Chen, Xuejuan Lin, Candong Li, Tetsuya Asakawa   +8 more
doaj   +1 more source

hbc/Molecular-convergence-between-Down-syndrome-and-Fragile-X-syndrome-hPSCs:

, 2022
Code repository for the paper "Molecular convergence between Down syndrome and Fragile X syndrome identified using human pluripotent stem cell ...
Victor Barrera
core   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Exploring differences in the human gut microbiome between Han Chinese and non-Chinese populations

Genome Biology
Background The human gut microbiota exhibits significant diversity across populations, influenced by factors such as geography, diet, and lifestyle, particularly between the Han Chinese and non-Chinese populations.
Jingjing Wang, Zhenmiao Zhang, Yang Chen, Xi Zhou, Jiaxin Xiang, Chao Yang, Dmitry A. Rodionov, Andrei L. Osterman, Qinwei Qiu, Yusheng Deng, Yanmin Liu, Chengrui Wang, Xiaoxiao Shang, Li Huang, Chen Sun, Jianwen Guo, Zhimin Yang, Lixiang Zhai, Zhaoxiang Bian, Aiping Lyu, Lijuan Han, Wei Jia, Xiaodong Fang, Lu Zhang   +23 more
doaj   +1 more source

Syndrome in Question [PDF]

Anais Brasileiros de Dermatologia, 2014
Multiple autoimmune syndrome is a rare condition, described by Humbert and Dupond in 1988. It is defined by the association of at least 3 autoimmune diseases in the same patient. Vitiligo is the most common skin condition in this syndrome. This article presents the case of a 31-year-old male with vitiligo, alopecia areata, Crohn's disease, psoriasis ...
Santos, Guida, Sousa, Lourdes
openaire   +6 more sources

Clinical manifestations of Deletion 22q11.2 syndrome (DiGeorge/Velo-CardioFacial syndrome) [PDF]

, 2005
Deletion 22q11.2 syndrome (Del22) (DiGeorge/Velo-Cardio-Facial syndrome) is characterized by congenital heart defect (CHD), palatal anomalies, facial dysmorphisms, neonatal hypocalcemia, immune deficit, speech and learning disabilities. CHD is present
Marino, Bonnie, Capolino, Rossella, Digilio, Maria Cristina, Dallapiccola, B.   +3 more
core  

The development of metaphorical language comprehension in typical development and in Williams syndrome [PDF]

, 2010
The domain of figurative language comprehension was used to probe the developmental relation between language and cognition in typically developing individuals and individuals with Williams syndrome.
Thomas, Michael S.C., Mareschal, Denis, Ansari, D., Purser, Harry, van Duuren, M., Karmiloff-Smith, Annette   +5 more
core   +1 more source

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

Understandings of Down's syndrome and their place in the prenatal testing context [PDF]

, 2003
INTRODUCTION: There is a growing consensus that decisions about prenatal testing should a) be informed, and b) reflect the individual's attitudes and values.
Bryant, Louise Dorothy
core   +5 more sources