Results 81 to 90 of about 4,352,139 (301)
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
The Turkish Journal of Pediatrics, 2017 Febrile infection-related epilepsy syndrome (FIRES) is a catastrophic epilepsy syndrome which is characterized by acute onset of refractory status epilepticus following a febrile infection occurring in previously normal children.
Caner Alparslan +5 more
doaj +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
PharmaceuticalsMyocardial infarction (MI) is a leading cause of heart failure, characterized by adverse cardiac remodeling. This study evaluated the cardioprotective potential of Dohongsamul-tang (DHT), a traditional Korean herbal formula, in a rat model of MI-induced ...
Youn-Jae Jang +6 more
doaj +1 more source
Change of differential diagnosis tactics in the process of clinical observation ofa patient
Бюллетень сибирской медицины, 2008 The complicated ratios of clinical symptoms of internal lesions during central lung cancer are demonstrated in the article when changes of differential diagnosis tactics were required for diagnosing that necessary keeping is priority of the clinical ...
O. V. Kalinina
doaj +1 more source
Case Reports Kabuki Syndrome in a Sri Lankan baby
, 2014 Kabuki syndrome (KS), also known as Kabuki ...
Kms Or Niikawa Kuroki Syndrome
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
BMC NephrologyBackground There is a need for a user-led, evidence-based digital application (app.) that meets the identified information and support needs and preferences of young people and young adults aged 12–35 years (YP/YA) with Nephrotic Syndrome (NS) in the ...
Moin A. Saleem +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Drug Design, Development and TherapyTingyao Zhao,1– 3 Huili Liao,1– 3 Rongfei Wang,1– 3 Bodi Xiao,1– 3 Zhaocong Li,1– 3 Fangyuan Qu,1– 3 Minqi Lu,1– 3 Zhongqi Yang,1– 3 Shihao Ni,1– 3 Xinting Wang1– 31State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated ...
Zhao T +9 more
doaj