Results 41 to 50 of about 15,839,975 (319)

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

Combining Chemical Permeation Enhancers for Synergistic Effects

European Journal of Drug Metabolism and Pharmacokinetics, 2015
Currently, macromolecular drugs such as proteins are mainly administered by means of injections due to their low intestinal epithelial permeability and poor stability in the gastrointestinal tract. This study investigated binary combinations of chemical drug absorption enhancers to determine if synergistic drug absorption enhancement effects exist ...
Trizel du Toit, Maides M. Malan, Hendrik J. R. Lemmer, Chrisna Gouws, Marique E. Aucamp, Wilma J. Breytenbach, Josias H. Hamman   +6 more
openaire   +3 more sources

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Preparation and Characterization of Hybrid Nanocomposites for Dental Applications

Applied Sciences, 2019
The study involved research related to the selection of the material with improved functional properties that can be used for dental prostheses. An innovative system of nanofillers, that differ in shape, by means of gelatin-modified halloysite nanotubes (
Katarzyna Gawdzinska, Sandra Paszkiewicz, Elzbieta Piesowicz, Katarzyna Bryll, Izabela Irska, Agnieszka Lapis, Ewa Sobolewska, Agnieszka Kochmanska, Wojciech Slaczka   +8 more
doaj   +1 more source

Tungsten-decorated MoP nanobelts for boosted hydrogen production

Materials Research Express, 2020
To further improve the electrochemical catalytic performance of MoP for hydrogen generation, a tungsten decoration strategy is proposed in this work, and the effect of preparation temperature was also investigated.
Dezhi Wang, Yao Lu, Kangyan Lv, Zhuangzhi Wu   +3 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Investigation of Antifungal Effects of Propolis and Curcumin Extracts on Trichophyton Species

Namık Kemal Tıp Dergisi, 2020
Aim: Trichophyton is the most common genus that causes superficial fungal infections among dermatophytes. The insufficiency of antifungal agents in the treatment of these species has led to the investigation of different therapeutic agents. In this study,
Zehra Özlem ÜNAL1, Berna ERDAL
doaj   +1 more source

Synergistic effects of GABA and hypoglycemic drugs

Problems of Endocrinology, 2023
Diabetes mellitus (DM) is the leading cause of premature death and disability. Despite a significant number of drugs, the effectiveness of therapy aimed at normalizing the level of glycemia and preventing complications does not fully satisfy doctors and patients.
I. N. Tyurenkov, T. I. Faibisovich, D. A. Bakulin   +2 more
openaire   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Advances of Synergistic Electrocatalysis Between Single Atoms and Nanoparticles/Clusters

Nano-Micro Letters
Highlights Fundamental principles for designing synergistic composite catalysts are reviewed. The synergistic effect between various active sites, promoting electrocatalytic performance in different reactions are highlighted.
Guanyu Luo, Min Song, Qian Zhang, Lulu An, Tao Shen, Shuang Wang, Hanyu Hu, Xiao Huang, Deli Wang   +8 more
doaj   +1 more source