Results 41 to 50 of about 957,593 (356)

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

The synergistic antitumor effect of Huaier combined with 5-Florouracil in human cholangiocarcinoma cells

BMC Complementary and Alternative Medicine, 2019
Background 5-Florouracil (5-FU) is a commonly used chemotherapeutic drug for cholangiocarcinoma, whereas it has unsatisfactory effect, and patients often have chemo-resistance to it.
Zhaoyu Fu, Kexin Ma, Bing Dong, Chongyu Zhao, Chi Che, Chengyong Dong, Rixin Zhang, Haibo Wang, Xiang Wang, Rui Liang   +9 more
doaj   +1 more source

Original Multivalent Gold (III) and Dual Gold(III)-Copper(II) Conjugated Phosphorus Dendrimers as Potent Antitumoral and Antimicrobial Agents [PDF]

, 2017
Original metallophosphorus dendrimers (generation 3, 48 terminal groups) have been prepared via the complexation of phosphorus dendrimers bearing imino-pyridino end groups with Au(III) or with both Au(III) and Cu(II).
Serge M. Mignani, Nabil El Brahmi, Saïd El Kazzouli, Regis Laurent, Sonia Ladeira, Anne-Marie Caminade, Elzbieta Pedziwiatr-Werbicka, Eligia M. Szewcyk, Maria Bryszewska, Mosto M. Bousmina, Thierry Cresteil, Jean Pierre Majoral   +11 more
core   +2 more sources

Personalizing the Pediatric Hematology/Oncology Fellowship: Adapting Training for the Next Generation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein, Melissa J. Rose, Scott Moerdler, Richard Ho   +3 more
wiley   +1 more source

Synergistic Model of Cardiac Function with a Heart Assist Device [PDF]

, 2019
The breakdown of cardiac self-organization leads to heart diseases and failure, the number one cause of death worldwide. The left ventricular pressure–volume relation plays a key role in the diagnosis and treatment of heart diseases.
Bestel, Haken, Knudsen, Simaan, Tuzun
core   +2 more sources

Synergistic Antifungal Study of PEGylated Graphene Oxides and Copper Nanoparticles against Candida albicans [PDF]

, 2020
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).The coupling ...
Arce, Mariana, Benito, Alejandro, Cerpa-Naranjo, Arisbel, Chen, Daijie, Cheong, Yuen Ki, Crisóstomo, Noemi Luengo, Kerai, Laxmi, Ren, Guogang, Rodríguez, Guillermo, Vadalia, Mansukhlal, Valverde, José L.   +10 more
core   +3 more sources

Combining Chemical Permeation Enhancers for Synergistic Effects

European Journal of Drug Metabolism and Pharmacokinetics, 2015
Currently, macromolecular drugs such as proteins are mainly administered by means of injections due to their low intestinal epithelial permeability and poor stability in the gastrointestinal tract. This study investigated binary combinations of chemical drug absorption enhancers to determine if synergistic drug absorption enhancement effects exist ...
Trizel du Toit, Maides M. Malan, Hendrik J. R. Lemmer, Chrisna Gouws, Marique E. Aucamp, Wilma J. Breytenbach, Josias H. Hamman   +6 more
openaire   +3 more sources

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Synergistic Effect and Phase Behavior of SCG-CAPB-H₂O Ternary Compound System

Applied Sciences
The physical properties of sodium cocoyl glycinate (SCG) and the synergistic effects within the SCG/CAPB complex system were investigated using visible–ultraviolet spectrophotometry and a surface tension meter.
Zhendong Zhu, Jiahao Zhang, Feihong Wang, Wenhui Feng, Leping Dang, Hongyuan Wei   +5 more
doaj   +1 more source

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source