Results 81 to 90 of about 15,839,975 (319)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Agronomic and Economic Interactions between Sidedressed Nitrogen and Potassium Fertilizations on ‘Atlantic’ Potato [PDF]
Nitrogen (N) and potassium (K) in potato crop planting synergistically increase tuber yield, but there are no studies on this interaction in sidedressing. In two experiments with ‘Atlantic’ potato combinations of four N rates (0, 50, 100, and 150 kg ha-1)
Renato Yagi +2 more
doaj +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Synergistic Effect of Some Emulsifiers
The synergistic antioxidant effects of the fatty acid esters of polyglycerol, propylene glycol and sorbitan with tocopherol (Toc) on lard and palm oil were investigated by the oven and AOM tests. The same tests were also carried out on lecithin.1) In the oven test, fatty acid esters of polyglycerol and sorbitan showed slight antioxidant effects on lard,
Minoru AOYAMA +6 more
openaire +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Synergistic Effect of Butyl Caffeate
Synergistic antioxidant effects of butyl caffeate (BC) and mixed tocopherol concentrate (m- Toc) on lard and palm oil were investigated by the oven test at 60°C and AOM test. The antioxidant effect of BC was also studied. BC was synthesized from caffeic acid and n-butyl alcohol, and its purity was found to be 94.5% by HPLC.1) On lard, BC showed strong ...
Minoru AOYAMA +5 more
openaire +2 more sources
Synergistic Antifungal Effect of Glabridin and Fluconazole
The incidence of invasive fungal infections is increasing in recent years. The present study mainly investigated glabridin (Gla) alone and especially in combination with fluconazole (FLC) against Cryptococcus neoformans and Candida species (Candida albicans, Candida tropicalis, Candida krusei, Candida parapsilosis and Candida Glabratas) by different ...
Wei Liu +10 more
openaire +4 more sources
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Revitalization as a synergistic effect
The development of modern cities is carried out in two main directions – expanding the suburban structures and restoring the life of the existing building areas. The growing problem that appears in discussions about the city is the revitalization, as evidenced by the fact of the entry into force October 9th 2015 the Act on revitalization.
openaire +3 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source

