Results 151 to 160 of about 9,227,129 (320)

Impact of the dual pilot policy of Smart Cities and Broadband China strategy on air pollution reduction in China

Discover Sustainability
The strategies of Smart Cities and Broadband China are pivotal policy arrangement for propelling the development of China's digital economy. Accurately assessing their synergistic impact on urban air pollution provides vital insights for flexibly ...
Jingrui Zhao, Genlong Guo
doaj   +1 more source

An Analysis of the Synergistic Effects of Air Pollutant Reduction and Carbon Mitigation in Major Emission Reduction Policies in China’s Transportation Sector

Energies
As of 2023, China’s transportation energy carbon emissions account for over 10%, which has a significant impact on achieving “dual carbon” goals. China has successively issued various policies to address pollution emissions in the transportation industry.
Jingan Zhu, Ping Jiang, Yuanxiang Chen
doaj   +1 more source

A comparative investigation of seed storage protein fractions: The synergistic impact of molecular properties and composition on anisotropic structuring

Food Hydrocolloids, 2022
Farzaneh Nasrollahzadeh, Laura Roman, Kasper Skov, L. M. Jakobsen, Binh Minh Trinh, E. Tsochatzis, Tizazu H. Mekonnen, M. Corredig, J. Dutcher, Mario M. Martinez   +9 more
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Unlocking Urban Breathability: Investigating the Synergistic Mitigation of PM_2.5 and CO₂ by Community Park Green Space in the Built Environment Using Simulation

Buildings
Reducing carbon emissions and controlling air pollution is a dual challenge for China in addressing climate change. Analyzing the synergistic relationship between PM2.5 and CO2 in urban green spaces has become an important part of promoting pollution ...
Xina Ma, Mengyao Wang, Xiaoling She, Jingyuan Zhao   +3 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Do aging, drinking, and having unhealthy weight have a synergistic impact on semen quality?

Journal of Assisted Reproduction and Genetics, 2021
N. Ramírez, G. Estofan, A. Tissera, R. Molina, E. Luque, P. J. Torres, A. Mangeaud, A. Martini   +7 more
semanticscholar   +1 more source