Results 61 to 70 of about 604,960 (300)

Can digitalization and low-carbonization progress in harmony? Evidence from Chinese cities.

PLoS ONE, 2023
Achieving high-quality development of the city requires actively promoting coordinated digitalization and low-carbon development. Previous studies have focused on the unidirectional impact of urban digitalization on low-carbonization and there is a lack ...
Siliang Guo
doaj   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason, John P. Woodhouse, Joanna S. Yi, M. Monica Gramatges, Olga A. Taylor, Veronica A. Morales, Shalini Dhamodharan, Marley Roberts, Karen R. Rabin, Philip J. Lupo, Michael E. Scheurer, Van Huynh, Steven D. Mittelman, Etan Orgel, Austin L. Brown   +14 more
wiley   +1 more source

Synergistic Relationship, Agent Interaction, and Knowledge Coupling: Driving Innovation in Intelligent Construction Technology

Buildings
The core driving force behind innovation in intelligent construction technology is synergistic relationships. It has become common practice to promote synergistic innovation through agent interaction and knowledge coupling in the development of ...
Wei Chen, Mingyu Yu, Jia Hou
doaj   +1 more source

Interplay of space radiation and microgravity in DNA damage and DNA damage response [PDF]

, 2017
In space, multiple unique environmental factors, particularly microgravity and space radiation, pose constant threat to the DNA integrity of living organisms.
Lu, Tao, Moreno-Villanueva, María, Wong, Michael, Wu, Honglu, Zhang, Ye   +4 more
core   +2 more sources

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich, Manali Zope, Peter M. Fantozzi, Cassie N. Kline, Iris Paltin, Matthew C. Hocking   +5 more
wiley   +1 more source

Synergistic effects of pollution reduction and carbon mitigation from socioeconomic factors, land use and urban innovation: a case study of Wuhan metropolitan area

Frontiers in Environmental Science
Achieving synergistic effects in pollution reduction and carbon mitigation is a major national strategy for China. Given the common origins and processes of air pollutants and greenhouse gases, this study constructs a theoretical framework for the study ...
Tao Chen, An Chen, Lanjun Liu, Chenxi Shi, Junzhe Zhang   +4 more
doaj   +1 more source

Developing an Agent-Based Drug Model to Investigate the Synergistic Effects of Drug Combinations

Molecules, 2017
The growth and survival of cancer cells are greatly related to their surrounding microenvironment. To understand the regulation under the impact of anti-cancer drugs and their synergistic effects, we have developed a multiscale agent-based model that can
Hongjie Gao, Zuojing Yin, Zhiwei Cao, Le Zhang   +3 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Can market-oriented environmental regulation achieve synergistic reduction of atmospheric pollution and carbon emissions? Evidence from China's carbon emissions trading policy

Cleaner Environmental Systems
Promoting the synergistic reduction of atmospheric pollution and carbon emissions is of great significance for China to achieve its emission reduction commitments.
Yuechao Zhao, Yin Feng, Jun Shen, Yijie He   +3 more
doaj   +1 more source