Results 71 to 80 of about 604,960 (300)

Complex interplay of kinetic factors governs the synergistic properties of HIV-1 entry inhibitors. [PDF]

, 2017
The homotrimeric HIV-1 envelope glycoprotein (Env) undergoes receptor-triggered structural changes that mediate viral entry through membrane fusion. This process is inhibited by chemokine receptor antagonists (CoRAs) that block Env-receptor interactions ...
Ahn, Koree W., Root, Michael J.
core   +2 more sources

Co-inhibition of EGFR and IGF1R synergistically impacts therapeutically on adrenocortical carcinoma

Oncotarget, 2016
Adrenocortical carcinoma (ACC) is a rare tumor with very poor prognosis and no effective treatment. The aim of this study was to explore a novel therapy co-targeting EGFR and IGF1R in vitro and vivo.The expression of EGFR and IGF1R were evaluated in a series of adrenocortical tumors by immunohistochemistry.
Xu, Lieyu, Qi, Yicheng, Xu, Yunze, Lian, Jianpo, Wang, Xiaojing, Ning, Guang, Wang, Weiqing, Zhu, Yu   +7 more
openaire   +2 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Advances in catalysts for synergistic elimination of VOCs and NO_x

能源环境保护
VOCs and NO_x are precursors of PM_2.5 and ozone, which can pose a severe threat to both the environment and human health. Catalytic technology is considered a promising multi-pollution treatment for the synergistic elimination of VOCs and NO_x, and is ...
WANG Zhuo, CHU Peiqi , WEI Lu* , LIU Yuxi, DAI Hongxing, DENG Jiguang*   +5 more
doaj   +1 more source

IRBIT a Master Regulator of Cell Physiology [PDF]

, 2017
(excerpt) Hormones and neurotransmitters regulate cell functions by binding to their receptors, which activate intracellular signaling and produce the physiological response [1].
Bouyer, Patrice G, Cook, Kelli, Petreska, Natasa   +2 more
core   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

SYNERGETIC IMPACT OF RISKS OF INVESTMENT PROJECTS IN POWER GENERATION BY THE TYPES

Ekonomìčnij Vìsnik Nacìonalʹnogo Tehnìčnogo Unìversitetu Ukraïni "Kiïvsʹkij Polìtehnìčnij Institut", 2015
The article focuses on the importance of evaluating the synergistic impact of project risks for different types of power generation companies in the course of qualitative analysis.
Рената Сергіївна Яресько
doaj   +1 more source

Creation and study of formulations as inhibitors of metal corrosion and scaling for stabilization water treatment in water utilization systems (a review) [PDF]

, 2016
This review summarizes studies for the past 5 years aimed at creation of efficient organophosphonate reagents for the stabilization water treatment aimed at preventing metal corrosion and scaling in water utilization systems.This study was carried out ...
Bolt, Y. V., Dernovaya, E. S., Driker, B. N., Fetisova, T. S., Tsirulnikova, N. V.   +4 more
core  

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Maml1 acts cooperatively with Gli proteins to regulate Sonic hedgheog signaling pathway [PDF]

, 2017
Sonic hedgehog (Shh) signaling is essential for proliferation of cerebellar granule cell progenitors (GCPs) and its misregulation is linked to various disorders, including cerebellar cancer medulloblastoma.
BELLAVIA, Diana, BUFALIERI, FRANCESCA, CHECQUOLO, Saula, DI MARCOTULLIO, LUCIA, FELLI, MARIA PIA, LAUER, DIETER MATTHIAS, NARDOZZA, FRANCESCA, PALERMO, ROCCO, PELULLO, MARIA, QUARANTA, ROBERTA, SCREPANTI, Isabella, TALORA, Claudio, VACCA, Alessandra, ZEMA, SABRINA   +13 more
core   +1 more source