Results 111 to 120 of about 771,131 (233)

A practical difference from the normal approach to evaluate natural killer (NK) cells and NK cell neoplasms by flow cytometry

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Natural killer (NK) cell neoplasms span indolent to highly aggressive entities, and flow cytometric immunophenotyping is central to their detection and classification. However, distinguishing reactive from neoplastic NK cell expansions can be challenging because NK cells lack somatically recombined antigen receptors, and reactive states may ...
Aaron J. Wilk, Afshin Shameli, Erik Ames, Jonathan R. Fromm, Bartosz Grzywacz, Min Shi, Sindhu Cherian, Jean Oak   +7 more
wiley   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Genetic variants of EcPV2 E6 and E7 in equine genital and oronasal squamous cell carcinoma

Equine Veterinary Journal, EarlyView.
Abstract Background Since its discovery in 2008, equine papillomavirus type 2 (EcPV2) has been detected in up to 100% of equine genital and up to 40% of equine oronasal squamous cell carcinomas (SCCs). Preliminary sequence data point to the existence of EcPV2 E6 and E7 oncogene variants compared to the British reference sequence from 2008.
Maya Jenner, Sabine Brandt
wiley   +1 more source

K-13 propeller gene polymorphisms isolated between 2014 and 2017 from Cameroonian Plasmodium falciparum malaria patients.

PLoS ONE, 2019
The emergence of artemisinin-resistant parasites since the late 2000s at the border of Cambodia and Thailand poses serious threats to malaria control globally, particularly in Africa which bears the highest malaria transmission burden.
Carole Else Eboumbou Moukoko, Fang Huang, Sandrine Eveline Nsango, Loic Pradel Kojom Foko, Serge Bruno Ebong, Patricia Epee Eboumbou, He Yan, Livia Sitchueng, Bouba Garke, Lawrence Ayong   +9 more
doaj   +1 more source

Molecular modeling data of KRAS exon 4 non-synonymous mutations.

, 2014
Molecular modeling data of KRAS exon 4 non-synonymous mutations.
Abdulaziz Al-Quorain (664096), Dalal M. Al-Tamimi (664095), Walid M. Naser (664094), Omar M. E. Albagha (664098), Mohamed A. Shawarby (291939), Areej M. Al Nemer (664097), Arun Seth (198633)   +6 more
core   +1 more source

Infection mechanisms of Rhizoctonia cerealis in wheat

iMeta, EarlyView.
We discover that R. cerealis (Rc) is a primary pathogen causing sharp eyespot of wheat after 335 distinct isolates were isolated from 1683 SE‐diseased wheat plants across China over 7 years using a single hyphal tip isolation method. We then generated high‐quality reference genomes via de novo sequencing of five representative Rc isolates and ...
Yan Ren, Ti Liu, Heying Zhao, Qirun Qian, Lufei Cui, Zhipeng Sun, Wenkai Yang, Peng Guo, Sisheng Wang, Lingran Zhang, Congwei Sun, Aolin Jia, Ning Zhang, Feng Chen   +13 more
wiley   +1 more source

Linear regression analysis of the relatedness between high/low frequency mutation loads and respective total mutation loads, i.e., synonymous and nonsynonymous mutations (A), nonsynonymous mutations (B) and synonymous mutations (C).

, 2014
Linear regression analysis of the relatedness between high/low frequency mutation loads and respective total mutation loads, i.e., synonymous and nonsynonymous mutations (A), nonsynonymous mutations (B) and synonymous mutations (C).
Yanjuan Xu (371985), Xiaofeng Fan (46577), Xiaoan Zhang (581220), Weihua Wang (196992), George M. Weinstock (43281), Adrian M. Di Bisceglie (243315)   +5 more
core   +1 more source

Protein Glutamylation: From Cytoskeleton to Signaling

Med Research, EarlyView.
Tubulin glutamylation, γ‐glutamylation, and nontubulin glutamylation are distinct yet interconnected post‐translational modifications that regulate diverse physiological and pathological processes, including cytoskeletal organization, cell cycle progression, immunity, metabolism, and disease development.
Jiayuan Chen, Yi Yuan, Qingquan Yu, Xinyue Wang, Hui Wang   +4 more
wiley   +1 more source

Overall, synonymous and non-synonymous mutations for different genes/regions of the five-level ploidy M. anguillicaudatus.

, 2014
Overall, synonymous and non-synonymous mutations for different genes/regions of the five-level ploidy M. anguillicaudatus.
Junjie Wu (393541), Xiujie Zhang (538959), Yongyao Yu (538958), Yanhe Li (153314), Xiaoyun Zhou (119506), Xianwu Guo (33484), Weimin Wang (145168)   +6 more
core   +1 more source

DNAJC13 Variants Show No Robust Association With Parkinson's Disease in a Multiancestry Cohort

Movement Disorders, EarlyView.
Abstract Background DNAJC13 was initially linked to autosomal dominant (AD) Parkinson's disease (PD) in a European Mennonite family carrying the p.N855S variant. However, imperfect segregation and conflicting reports of pathogenicity raised uncertainty of the role of DNAJC13 in the disease.
César Luis Ávila, Mariam Isayan, Yasser Mecheri, Paula Saffie‐Awad, María Milagros Leila, Laurel A. Screven, Hampton Leonard, Maria Teresa Periñan, Sheila Yeboah, Kristin Levine, Mary B. Makarious, on behalf of the Global Parkinson's Genetics Program (GP2)   +11 more
wiley   +1 more source