Results 211 to 220 of about 771,131 (233)

Synonymous mutations and the molecular evolution of SARS-Cov-2 origins

, 2020
Wang H, Pipes L, Nielsen R.
europepmc   +1 more source

Genome‐Wide Association Study Elucidates the Genetic Architecture of Manganese Tolerance in Brassica napus

Plant, Cell &Environment, EarlyView.
ABSTRACT Brassica napus (canola) is a significant contributor to the world's oil production and is cultivated across continents, yet acidic soils with aluminium (Al3+) and manganese (Mn2+) toxicities limit its production. The genetic determinants underlying natural variation for acidic soil tolerance in canola are unknown and need to be determined ...
Harsh Raman, Zetao Bai, Brett McVittie, Sourav Mukherjee, Hugh D. Goold, Yuanyuan Zhang, Nay Chi Khin, Yu Qiu, Nawar Shamaya, Shengyi Liu, Regine Delourme, Barry J. Pogson, Sureshkumar Balasubramanian, Rosy Raman   +13 more
wiley   +1 more source

Hidden Strategies Beneath a Single Nucleotide: Contrasting Physiology in Lichen Photobiont Strains

Plant, Cell &Environment, EarlyView.
ABSTRACT Lichen photobionts exhibit significant physiological variability with important ecological implications. While this variability is relatively well studied at the interspecific level, it has rarely been examined at the intraspecific level. Here, we investigated the physiological responses to temperature and irradiance of two Trebouxia lynniae ...
Miguel Blázquez, David Pizarro, Ana García‐Muñoz, Raquel Pino‐Bodas, Asunción de los Ríos, Miren I. Arzac, José Ignacio García‐Plazaola, Beatriz Fernández‐Marín, Unai Artetxe, Rosa Toledo‐Gil, Fernando Vallejo, Leonardo M. Casano, Israel Pérez‐Vargas, Sergio Pérez‐Ortega, Francisco Gasulla   +14 more
wiley   +1 more source

UV signature mutation hyperhotspots as genomic dosimeters

Photochemistry and Photobiology, EarlyView.
Recurrent UV signature mutations are a sensitive and specific indicator of sun exposure. UV signature mutations (C → T mutations at dipyrimidine sites) were quantified using Duplex Sequencing and a stringent mutation calling protocol to identify true low‐abundance mutations.
Vijay Menon, Alejandro García‐Ruiz, Susan Neveu, Brenda Cartmel, Leah M. Ferrucci, Meg Palmatier, Christine Ko, Kenneth Y. Tsai, Mio Nakamura, Sa Rang Kim, Michael Girardi, Karl Kornacker, Douglas E. Brash   +12 more
wiley   +1 more source

SARS-CoV-2 and ORF3a: Non-Synonymous Mutations and Polyproline Regions

, 2020
Issa E, Merhi G, Panossian B, Salloum T, Tokajian S.   +4 more
europepmc   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Deciding What to Believe or Deciding What to Do? An Empirical Investigation of the Folk Conception of Critical Thinking

Theoria, EarlyView.
ABSTRACT This study investigates how the expression ‘critical thinking’ (CT) is understood and used by the general public in the United States, using the tools of experimental philosophy. Based on responses from 288 non‐philosopher participants, our findings suggest that CT is commonly associated with problem solving, decision making and logical ...
Céline Schöpfer, Julia Ghaliounghi, Florian Cova   +2 more
wiley   +1 more source

Investigating the molecular basis of the serological Rh D‐negative phenotype in Indonesia: nature, frequency, and impact for diagnostics

Transfusion, EarlyView.
Abstract Background Although widely studied and reported for more than 30 years, the molecular basis of Rh D‐negativity has remained unexplored in several regions of the world, including in Indonesia, Southeast Asia. Study Design and Methods A subset of 436 Indonesian blood donors originally typed D‐negative (D–) by routine serological testing was ...
Tonny Wongso, Teguh Triyono, Caroline Bénech, Gauthier Thomas, Sasi Widuri, Martono Adi Triyogo, Ni Kadek Mulyantari, Misnah Syarifuddin, Halimi Maksum, Winda Astuti Taruno, Hasna Fadlilatul Bidayah, Yann Fichou   +11 more
wiley   +1 more source

Compensating the Fitness Costs of Synonymous Mutations.

Molecular Biology and Evolution, 2016
Synonymous mutations do not change the sequence of the polypeptide but they may still influence fitness. We investigated in Salmonella enterica how four synonymous mutations in the rpsT gene (encoding ribosomal protein S20) reduce fitness (i.e.
Dan Andersson, Joakim Näsvall, Anna Knöppel   +2 more
exaly   +2 more sources

Synonymous Mutations Frequently Act as Driver Mutations in Human Cancers [PDF]

Cell, 2014
SummarySynonymous mutations change the sequence of a gene without directly altering the sequence of the encoded protein. Here, we present evidence that these “silent” mutations frequently contribute to human cancer.
Juan Valcárcel, Fran Supek, Ben Lehner
exaly   +2 more sources