Results 41 to 50 of about 25,748 (298)

Spatial Control Over Tether‐Tunable Coordination on Palladium for Divergent Synthesis of Bicyclo[n.1.0]alkanes via Oxidative Cyclopropanation of Enynes

Advanced Science, EarlyView.
We have developed a Pd‐catalyzed oxidative cyclopropanation of 1,n‐enynes employing cyclic diacyl peroxides as bifunctional reagents that serve as both tether‐tunable oxidants and spatially controlled dicarboxylate anions. ABSTRACT Bicyclo[n.1.0]alkanes are highly valuable scaffolds in drug discovery and synthetic chemistry.
Ting Yuan, Lei Shi
wiley   +1 more source

Evidence-based alignment of conservation policies with remote sensing-enabled essential biodiversity variables

Ecological Indicators, 2021
Nature conservation policies require up-to-date and accurate biodiversity monitoring. Innovative synoptic information products such as Remote Sensing-enabled Essential Biodiversity Variables (RS-enabled EBVs) could complement field observations in ...
M.C. Lock, A.K. Skidmore, I. van Duren, C.A. Mücher   +3 more
doaj   +1 more source

Harnessing the Neurobiology of Empathy and Compassion to Alleviate Burnout in Neurology

Annals of Neurology, EarlyView.
The neurologist cares for patients with complex chronic conditions that compromise their wellbeing. Many such disorders are poorly understood. Whereas for some, effective symptomatic treatments exist, for most we lack an understanding of the molecular and cellular bases for disease pathogenesis needed for discovering disease‐modifying treatments ...
Fadel Zeidan, Joseph D. Stern, William C. Mobley   +2 more
wiley   +1 more source

Developing an Effective Enforcement System for a Marine Reserve in the Pitcairn Islands [PDF]

, 2013
This paper details how monitoring and enforcement of the Pitcairn Island's exclusive economic zone could be effectively undertaken for a relatively low level of expenditure.

core  

Early Pliocene Varanus (Squamata, Varanidae) remains from Megalo Emvolon, Thessaloniki, Greece

The Anatomical Record, EarlyView.
The article describes new cranial and postcranial varanid material from Megalo Emvolon Lower Pliocene vertebrate fossil site near Thessaloniki. The fossils, likely representing a single individual, are referred to Varanus cf. marathonensis. Abstract This study describes new fossil varanid material from a recently discovered fossil spot (MVL site) at ...
Chara Drakopoulou, Georgios L. Georgalis, Georgios Lazaridis, Dimitris S. Kostopoulos   +3 more
wiley   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Major Publications in the Critical Care Pharmacotherapy Literature: 2021

Critical Care Explorations, 2022
OBJECTIVES:. To summarize the most impactful articles relevant to the pharmacotherapy of critically ill adult patients published in 2021. DATA SOURCE:. PubMed/MEDLINE. STUDY SELECTION:.
Patrick M. Wieruszewski, PharmD, Laura M. Brickett, PharmD, Lokesh Dayal, MD, Ashley M. Egan, MD, Ashish K. Khanna, MD, Steven M. Lemieux, PharmD, Satyanarayana R. Mukkera, MD, MPH, Jaimini S. Patel, PharmD, Michael J. Reichert, PharmD, Tessa R. Reynolds, PharmD, Parijat Sen, MD, Nathaniel M. Thornton, DNP, Gavin M. Turpin, DNP, Jessica B. Winter, PharmD, Brittany D. Bissell, PharmD, PhD   +14 more
doaj   +1 more source

Synoptic reporting by summarizing cancer pathology reports using large language models [PDF]

Npj Health Syst
AbstractBackgroundSynoptic reporting, the documenting of clinical information in a structured manner, is known to improve patient care by reducing errors, increasing readability, interoperability, and report completeness. Despite its advantages, manually synthesizing synoptic reports from narrative reports is expensive and error prone when the number ...
Rajaganapathy S, Chowdhury S, Li X, Buchner V, He Z, Zhang R, Jiang X, Yang P, Cerhan J, Zong N.   +9 more
europepmc   +3 more sources

Bridging home, school and community to address educational inequality: Supporting educational trajectories through community bridge work

British Educational Research Journal, EarlyView.
Abstract This paper explores the role of community stakeholders in supporting the educational trajectories of students experiencing socio‐economic disadvantage in the Irish context. Building on international and national policy debates, the study examines how community‐based organisations, statutory services and outreach initiatives work alongside ...
Aoife Joy Keogh, Deirdre McGillicuddy
wiley   +1 more source

Synoptic Versus Narrative Reporting of Prostate Biopsies at a Tertiary Healthcare Institution : Challenges, successes and expectations

Sultan Qaboos University Medical Journal, 2017
Objectives: Cancer pathology reports are expected to contain all information required for patient management and disease surveillance. Moreover, reports for patients with prostate cancer have become increasingly complex with the addition of more ...
Nnamdi O. Orah, Charles C. Anunobi, Rufus W. Ojewola   +2 more
doaj   +1 more source