Results 51 to 60 of about 10,785 (208)

Artemisinins in autoimmune diseases: effects and mechanisms in systemic lupus erythematosus and rheumatoid arthritis

British Journal of Pharmacology, EarlyView.
Abstract Autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) result from immune self‐tolerance loss, causing tissue damage. Standard treatments targeting late‐stage inflammation often have serious side effects. Artemisinin, known for its antimalarial properties, shows potential immunomodulatory effects.
Fanchao Zhou, Guoming Li, Ruixiang Tan, Guodong Wu, Changsheng Deng   +4 more
wiley   +1 more source

Real‐World Data Analysis of Genomic Alterations Detected by a Dual DNA–RNA Comprehensive Genomic Profiling Test

Cancer Science, EarlyView.
This study analyzed 1356 cases using GenMineTOP, Japan's first dual DNA–RNA CGP test, and identified oncogenic alterations in 91.5% of cases. The RNA panel detected 105 fusion events, including 11 NTRK fusions. Furthermore, the analysis clarified the independent effects of genomic abnormalities and cancer type on RNA expression, providing valuable ...
Kousuke Watanabe, Miho Ogawa, Aya Shinozaki‐Ushiku, Shuichi Tsutsumi, Kenji Tatsuno, Hiroyuki Aburatani, Hidenori Kage, Katsutoshi Oda   +7 more
wiley   +1 more source

JUXTAFACET CYST OF CERVICAL SPINE: A RARE NEURAL FORAMINAL LESION [PDF]

, 2010
Juxtafacet cysts (JFC) are well recognized entities occurring in the spine in relation to facet joints. These lesions include synovial cysts and ganglion cysts. Lumbar spine is more common location amongst other regions of the spine.
Hamid, Rana Shoaib, Khan, Zahid Anwar, Rehman, Imaad ur   +2 more
core   +1 more source

Intelligent Manufacturing for Osteoarthritis Organoids

Cell Proliferation, EarlyView.
Overall schematic of intelligent manufacturing in osteoarthritis organoids. Broad overview of the article's structure, outlining the progression from fundamental joint anatomy and OA pathogenesis to organoid construction and, ultimately, to intelligent manufacturing and future prospects.
Xukun Lyu, Jian Wang, Jiacan Su
wiley   +1 more source

Synovial pathology detected on ultrasound correlates with the severity of radiographic knee osteoarthritis more than with symptoms [PDF]

, 2014
OBJECTIVE: To [1] compare the frequency and severity of ultrasound (US) features in people with normal knees (controls), knee pain (KP), asymptomatic radiographic OA (ROA), and symptomatic OA (SROA), [2] examine relationships between US features, pain ...
Altman, Aspden, Ayral, Baker, Bedson, Bellamy, Benito, Berenbaum, Bevers, Chatzopoulos, D'Agostino, de Lange-Brokaar, de Miguel Mendieta, Doherty, Felson, Felson, Felson, Fiocco, Hannan, Hawker, Hayashi, Hill, Hill, Iagnocco, Ingham, Joshua, K. Latief, Kristoffersen, Lanyon, Limer, M. Doherty, M. Hall, Mermerci, Nagaosa, Naredo, O'Reilly, P. Courtney, Porta, Roemer, S. Doherty, Samuels, Schmidt, Simkin, Song, Spector, Tarhan, W. Zhang, Wakefield, Walsh, Walther, Wilkinson, Wu, Wu, Zhang   +53 more
core   +3 more sources

Diagnostic imaging and successful outcome of a lateral collateral ligament desmitis of the elbow joint

Equine Veterinary Education, EarlyView.
Summary A 13‐year‐old Belgian jumping mare was presented with acute onset of severe left forelimb lameness after a jumping competition. Radiographic evaluation showed the presence of periosteal bone formation on the lateral radial eminence, while ultrasonography revealed an injury of the lateral collateral ligament of the elbow associated with severe ...
E. Porzio, K. Guidoni, S. Fantoni, T. Bartolini, F. Beccati   +4 more
wiley   +1 more source

Potential role of the posterior cruciate ligament synovio-entheseal complex in joint effusion in early osteoarthritis: a magnetic resonance imaging and histological evaluation of cadaveric tissue and data from the Osteoarthritis Initiative [PDF]

, 2014
Objective: This study explored posterior cruciate ligament (PCL) synovio-entheseal complex (SEC) microanatomy to determine whether it may participate in the early osteoarthritis (OA) disease process.
A. Radjenovic, A.J. Freemont, Agha, Aigner, Ayral, Baker, Benjamin, Benjamin, Benjamin, Benjamin, Bentley, Binks, D. Bergin, D. McGonagle, D.A. Binks, Felson, Guermazi, Hasegawa, Hayashi, Hill, McGonagle, McGonagle, Mullaji, Myers, Peterfy, Peterfy, R.J. Hodgson, Roemer, Roemer, T. Yonenaga, Tan, Tan, Wolfe, Zhang   +33 more
core   +2 more sources

Acute severe lameness associated with proliferative bone on the dorsal middle phalanx (19 cases)

Equine Veterinary Education, EarlyView.
Summary Background Injury resulting in proliferative new bone formation on the dorsal aspect of the middle phalanx (P2) has been recognised by equine veterinarians and is generally referred to as capsulitis. However, no retrospective case series has been published on the condition. Objectives To describe the clinical features, treatment, and outcome of
J. G. Fowlie, H. D. O'Neill, F. A. Nickels, S. Mattson   +3 more
wiley   +1 more source

Paralabral cysts in the hip joint: findings at MR arthrography [PDF]

, 2018
Purpose: The purpose of this research was to retrospectively characterize paralabral cysts of the hip as seen at MR arthrography. Materials and methods: After Institutional Review Board approval, 704 patients who had MR arthrography were identified over ...
Bedi, Asheesh, Brigido, Monica, Fessell, David, Girish, Gandikota, Jacobson, Jon, Magerkurth, Olaf   +5 more
core  

Pain in patients with equal radiographic grades of osteoarthritis in both knees: the value of gray scale ultrasound [PDF]

, 2012
SummaryObjectivesTo investigate the association of ultrasound (US) features with pain and the functional scores in patients with equal radiographic grades of osteoarthritis (OA) in both knees.MethodsFifty-six consecutive patients with knee OA: 85 ...
Chern, T.-C., Jou, I.-M., Kuo, L.-C., Shao, C.-J., Wu, K.-C., Wu, P.-T., Wu, T.-T.   +6 more
core   +1 more source