Results 11 to 20 of about 16,784 (197)

PRAME and HLA Class I expression patterns make synovial sarcoma a suitable target for PRAME specific T-cell receptor gene therapy

OncoImmunology, 2018
Synovial sarcoma expresses multiple cancer testis antigens that could potentially be targeted by T-cell receptor (TCR) gene therapy. In this study we investigated whether PRAME-TCR-gene therapy could be an effective treatment for synovial sarcoma by ...
Sietse J Luk, Dirk M van der Steen, Renate S Hagedoorn, Ekaterina S Jordanova, Marco W Schilham, Judith VMG Bovée, Arjen HG Cleven, JH Frederik Falkenburg, Karoly Szuhai, Mirjam HM Heemskerk   +9 more
doaj   +1 more source

Primary Cardiac Synovial Sarcoma Presents as a Ventricular Mass and Renal Infarction

Annals of Internal Medicine: Clinical Cases, 2023
Synovial sarcoma (SS) is a rare type of soft tissue sarcoma (STS) that can occur anywhere in the body, most commonly presenting in the extremities. We present a primary cardiac synovial sarcoma (PCSS) case in a 22-year-old man who initially presented ...
Kimberly M. Hsu, Emily Seif
doaj   +1 more source

Synovial sarcoma of female urethra: a case report and review of the literature

Diagnostic Pathology, 2023
Synovial sarcoma (SS) is a rare malignant soft tissue sarcoma that originates from primitive mesenchymal cells with epithelial differentiation potential. It is most commonly found in the limbs and trunk.
Wei Cui, Yuan-Jian Liao, Peng Su, Hua Yang, Neng Zhang   +4 more
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A rare case of perineal synovial sarcoma

Radiology Case Reports, 2023
Synovial sarcoma is a malignant mesenchymal neoplasm that is frequently misdiagnosed due to its slow growth and small size. This tumor presents as a nonspecific heterogeneous mass on cross-sectional imaging.
Ho Xuan Tuan, MD, PhD, Tran Ngoc Dung, MD, Dau Quang Lieu, MD, Tran Bao Long, MD, Tran Ngoc Anh, MD, Luu Quang Dung, MD, Nguyen Minh Duc, MD   +6 more
doaj   +1 more source

Synovial Sarcoma Microvesicles Harbor the SYT-SSX Fusion Gene Transcript: Comparison of Different Methods of Detection and Implications in Biomarker Research

Stem Cells International, 2016
Background. Synovial sarcoma is an aggressive soft-tissue malignancy. This study examines the presence of the SYT-SSX fusion transcript in synovial sarcoma microvesicles as well as its potential role as a biomarker for synovial sarcoma.
A. Fricke, P. V. Ullrich, A. F. V. Cimniak, M. Follo, S. Nestel, B. Heimrich, I. Nazarenko, G. B. Stark, H. Bannasch, D. Braig, S. U. Eisenhardt   +10 more
doaj   +1 more source

Synovial sarcoma of the neck

Ortadoğu Tıp Dergisi, 2020
The paper describes the case of a 60-year-old male patient with a mass in the left jugulodigastric area, which was later identified as synovial sarcoma. Differential diagnoses such as cystic lesions, metastatic lymph nodes, and salivary gland tumors were considered.
Emre Emekli, Mustafa Fuat Açıkalın, Melek Kezban Gürbüz, Uğur Toprak   +3 more
openaire   +2 more sources

Primary synovial sarcoma of the prostate: A case report and literature review

Clinical Case Reports, 2022
Synovial sarcoma arising from the prostate is extremely rare. Synovial sarcoma of the prostate is usually identified at a late stage and makes the treatment challenging.
Ali Emadi Torghabe, Ramin Ebrahimi, Zohreh Pishevar Feizabad   +2 more
doaj   +1 more source

Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma

eLife, 2018
Synovial sarcoma tumours contain a characteristic fusion protein, SS18-SSX, which drives disease development. Targeting oncogenic fusion proteins presents an attractive therapeutic opportunity.
Gerard L Brien, David Remillard, Junwei Shi, Matthew L Hemming, Jonathon Chabon, Kieran Wynne, Eugène T Dillon, Gerard Cagney, Guido Van Mierlo, Marijke P Baltissen, Michiel Vermeulen, Jun Qi, Stefan Fröhling, Nathanael S Gray, James E Bradner, Christopher R Vakoc, Scott A Armstrong   +16 more
doaj   +1 more source

Synovial Sarcoma of the Extremities: A Literature Review

Applied Sciences, 2021
Synovial sarcoma (SS) is a rare and highly malignant tumor and a type of soft tissue sarcoma (STS), for which survival has not improved significantly in recent years.
Cosmin Ioan Faur, Daniel Laurentiu Pop, Ahmed Abu Awwad, Carmen Lacramioara Zamfir, Roxana Folescu, Daniela Gurgus, Andrei Gheorghe Marius Motoc, Jenel Marian Patrascu, Sorin Bogdan Motoi, Oana Belei, Ana Maria Ungureanu   +10 more
doaj   +1 more source

SYNOVIAL CELL SARCOMA [PDF]

Acta Medica Iranica, 1997
Ten cases of synovial cell sarcoma are reported. The youngest patient was a 2'A years old boy with synovial cell sarcoma of the knee and the oldest one was a man with synovial cell sarcoma of the elbow.
M. Farzan
doaj   +2 more sources