Results 111 to 120 of about 52,925 (287)

Multi‐Omics Reveal the Dysregulated Gut‐Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China

Advanced Science
Gut microbiota dysbiosis and associated host immuno‐metabolic disorders may play a role in knee synovitis. Herein, integrated multi‐omics analyses of stool and blood samples from subjects from Pearl River Osteoarthritis Cohort (PROC, N = 207) are ...
Xiaoshuai Wang, Yi Liu, Ziying Sun, Jia Li, Zhihao Lu, Jiayuan Huang, Shixian Hu, Peihua Cao, Xiaolong Cao, Shangru Li, Jianzhao Ruan, Jinhui Liu, Jingyu Xie, Haitao Sun, Tianyu Chen, Shengfa Li, Zhaohua Zhu, Zhibo Wen, Rocky S. Tuan, David John Hunter, Zhong Alan Li, Dongquan Shi, Changhai Ding   +22 more
doaj   +1 more source

Pigmented villonodular synovitis of the lumbosacral spine

, 2005
Pigmented villonodular synovitis commonly occurs in synovial joints of the appendicular skeleton but rarely affects the synovial joint of the spine, and thus information regarding its natural history, treatment and prognosis remains limited.
Aydinli U., Oztop F., Ozturk C., Yalcinkaya U.   +3 more
core   +1 more source

Smart Nanodelivery Systems for Immunometabolic Modulation in Osteoarthritis

Exploration, EarlyView.
Smart nanodelivery systems deliver therapeutic payloads across the cartilage matrix to ensure their sustained accumulation within chondrocytes at sites of injury. By targeting specific molecular targets and signaling pathways, these platforms modulate the pathological synovium‐cartilage axis to restore immunometabolic homeostasis and drive tissue ...
Qirui Zhao, Zhewen Mi, Shuya Liu, Shijun Liang, Linjia Peng, Zixuan Gao, Jiaming Li, Xiaoqing Lu, Zhiguang Ren, Yongjie Wan, Shengsheng Cui, Longlong Lu, Xiaoyang Gao, Tao Wang, Hui Liang, Furong Tian, de la Fuente Jesus M, Chong Xiang, Luyi Sun, Lichen Xiang, Daxiang Cui   +20 more
wiley   +1 more source

Pigmented Villonodular Synovitis in a Patient who Underwent Hip Arthroplasty

, 2014
Pigmented villonodular synovitis (PVNS) is a rare, benign, but a locally aggressive tumor. It is characterized by the proliferation of synovial membrane, but it can also be seen in tendon sheaths and bursae.
Nevzat Dabak, Alper Çıraklı, Bedri Kandemir, Hasan Göçer   +3 more
core  

Advanced Molecular Imaging Probes for Skeletal Diseases: Current Progress and Future Perspectives

iRADIOLOGY, EarlyView.
This review summarizes the potential molecular imaging techniques and probes for common orthopedic diseases, such as trauma, infection, metabolism, tumor, joint, spine and other fields, aiming to provide a basis for the development of a new generation of molecular imaging probes.
Shuo Guo, Yuling Cui, Zhiye Fan, Chenxin Jiang, Bowen Fu, Guangbin Cui, Yanli He   +6 more
wiley   +1 more source

Mapping Fatty Acid Composition in the Human Knee: Short‐Term Repeatability at 3T

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Alterations in periarticular lipid composition are implicated in musculoskeletal diseases, yet short‐term reliability of MRI‐based triglyceride composition mapping in the knee is not fully established. Purpose To evaluate 1‐week repeatability of proton‐density fat fraction (PDFF) and triglyceride fatty‐acid composition—saturated ...
Dimitri Martel, Anne Adlung, Baptiste Busi, Rollanda Bernadin, Yagni Shah, Thorsten Kirsch, Richard Kijowski, Guillaume Madelin, Amparo Ruiz   +8 more
wiley   +1 more source

Point‐of‐Care Ultrasound for the Diagnosis of Hip Effusion in Children Presenting to the Emergency Department With Atraumatic Limp or Hip Pain: A Scoping Review

Journal of Ultrasound in Medicine, EarlyView.
This study reviews the evidence for point‐of‐care ultrasound (POCUS) for the detection of hip effusion in children presenting to the emergency department with atraumatic limp or hip pain. A scoping review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses Extension for Scoping Review (PRISMA‐ScR) guideline ...
Nigel Chan, David J. McCreary, Adriana Nedyalkova, Peter J. Snelling   +3 more
wiley   +1 more source

B cells in rheumatoid synovitis.

, 2005
In rheumatoid arthritis, T cells, B cells, macrophages, and dendritic cells invade the synovial membranes, establishing complex microstructures that promote inflammatory/tissue destructive lesions.
Goronzy, Jörg J, Weyand, Cornelia M, Seyler, Thorsten M   +2 more
core   +1 more source

Radiosynovectomy in pigmented villonodular synovitis

, 2000
Summary Background: Pigmented villonodular synovitis (PVS) is a very rare disorder characterized by a slowly progressive benign proliferation of synovial tissue. As yet, the mainstay of its treatment has been surgical or athroscopic synovectomy.
R. Kutz, T. Elbracht, S. Kat, T. Kuwert, G. Weseloh   +4 more
core   +1 more source

USP7 Regulates TRPV1 Deubiquitination to Mediate Chondrocyte Ferroptosis and Alleviate Osteoarthritis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease characterized by chondrocyte dysfunction. In this study, we explored the function and mechanism of ubiquitin‐specific protease 7 (USP7) in chondrocyte ferroptosis in OA. The USP7, TRPV1, collagen II, and GPX4 levels in knee joint tissue were detected using immunohistochemistry ...
Jun Li, Ding Chen, Wei‐Ye Zhong
wiley   +1 more source