Results 121 to 130 of about 52,925 (287)

Safety profile comparison of intra‐articular corticosteroids, hyaluronic acid, platelet‐rich plasma, and cell‐based injections for knee osteoarthritis: A systematic review and meta‐analysis by the ESSKA Orthobiologics Initiative

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The aim was to compare the safety profiles of corticosteroids (CS), hyaluronic acid (HA), blood‐derived products based on platelet concentrates (for simplicity indicated as PRP ‐ platelet‐rich plasma ‐ being PRP the most common product), and cell‐based therapies (namely products exploiting the therapeutic function of mesenchymal ...
Alessandro Bensa, Andrea Piano, Giacomo Arthur Fumagalli, Laura de Girolamo, Lior Laver, Jérémy Magalon, Mikel Sánchez, Thomas Tischer, Giuseppe Filardo   +8 more
wiley   +1 more source

Synergistic Improvements in Synovitis, Enthesitis, and Patient-Reported Outcomes for Patients with Psoriatic Arthritis Treated with Ixekizumab in SPIRIT Trials

Rheumatology and Therapy
Introduction Synovitis and enthesitis are key manifestations in psoriatic arthritis (PsA). This descriptive analysis investigated the association between improvement in synovitis and enthesitis, individually and combined, and improvement in patient ...
Lars-Erik Kristensen, Dennis McGonagle, Martin Rudwaleit, Hideto Kameda, Peter Adler Würtzen, Marcus Ngantcha, Thorsten Holzkämper, Josef Smolen   +7 more
doaj   +1 more source

Glanzmann Thrombasthenia Associated with Siderotic Synovitis and Arthropathy: A Case Report

, 2023
Mouhammad J Alawad,1 Mohammad Abu-Tineh,2 Awni Alshurafa,2 Alaa Al-Taie,3 Anil Yousaf,2 Mohamed A Yassin2 1Department of Medical Education, Internal Medicine Residency Program, Hamad Medical Corporation, Doha, Qatar; 2Department of Medical Oncology ...
Abu-Tineh M, Yassin MA, Alawad MJ, Al-Taie A, Alshurafa A, Yousaf A   +5 more
core  

Collagen‐membrane‐covered matrix‐associated chondrocyte implantation improves safety over periosteum‐covered MACI for large knee cartilage defects: A real‐world data analysis in the registry study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This registry study aimed to evaluate the safety and effectiveness of collagen membrane‐covered matrix‐associated autologous chondrocyte implantation (cMACI) versus periosteum‐covered MACI (pMACI) for large knee cartilage defects (Outerbridge III–IV, ≥4 cm²) in the femorotibial and/or patellofemoral joints with a minimum 2‐year follow ...
Yuji Uchio, Ryosuke Kuroda, Yasuo Niki, Katsura Sugawara, Yasuyuki Ishibash   +4 more
wiley   +1 more source

Relation of synovitis to knee pain using contrast-enhanced MRIs

, 2010
Background: It has been suggested that synovitis causes joint pain. On non-contrast-enhanced MRIs synovial thickening cannot be assessed and on these images synovitis has been inconsistently associated with pain.
Hughes, L., Grainger, A., Buckwalter, J., Clancy, M., Wooley, A., Felson, D. T., Niu, J., Guermazi, A., Nevitt, M., Baker, Kristin, Crema, M.   +10 more
core   +1 more source

Quadriceps tendon autograft is not inferior to bone‐patellar tendon‐bone or hamstring autograft in anterior cruciate ligament reconstruction in terms of subjective patient‐reported outcomes: Two‐year results of a multicenter randomised controlled study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate the effectiveness of quadriceps tendon (QT) compared to bone‐patellar tendon‐bone (BPTB) and hamstring tendon (HT) autografts in anterior cruciate ligament reconstruction (ACLR) regarding patient‐reported outcomes 2 years postoperatively.
Barbara C. Boer, Reinoud W. Brouwer, Judith olde Heuvel, Astrid J. de Vries, Wybren A. van der Wal, J. Christiaan Rompen, Albert H. van Houten, Roy A. G. Hoogeslag   +7 more
wiley   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

Med Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei, Xiaoxian Lou, Xu Su, Shubao Liu, Yanli Tong, Jie Chen, Xuerui Chen, Wenjun Mao, Hui Yu, Liangbin Lin   +9 more
wiley   +1 more source

Validity of an ultrasonographic joint-specific scoring system in juvenile idiopathic arthritis: a cross-sectional study comparing ultrasound findings of synovitis with whole-body magnetic resonance imaging and clinical assessment

RMD Open
Objective To assess the validity of an ultrasonographic scoring system in juvenile idiopathic arthritis (JIA) by comparing ultrasound detected synovitis with whole-body MRI and clinical assessment of disease activity.Methods In a cross-sectional study ...
Anna-Birgitte Aga, Pernille Bøyesen, Berit Flatø, Vibke Lilleby, Nina Krafft Sande, Eva Kirkhus, Anders Høye Tomterstad   +6 more
doaj   +1 more source

Age‐related clinical heterogeneity and peripheral T cell profile alterations in primary Sjögren's disease: A retrospective study of 5778 patients

Rheumatology &Autoimmunity, EarlyView.
This large‐scale retrospective study of 5778 primary Sjögren's disease (SjD) patients, stratified by diagnostic age, defines a distinct clinical and immunological profile for early‐diagnosed (<45 years) disease. We identified early diagnosis as an independent risk factor for hypergammaglobulinemia and interstitial lung disease, underpinned by a ...
Yuan Ning, Ruiling Feng, Kai Zhang, Yipeng Han, Ruoyi Wang, Guangwen Li, Yuebo Jin, Jing He   +7 more
wiley   +1 more source

Persistent polyarticular synovitis after treatment with alendronate

, 2007
Udgivelsesdato: 2007-Apr-23A 62-year-old, previously healthy woman diagnosed with post-menopausal osteoporosis received alendronate 70 mg/week. One week after the first dose, she developed polyarticular synovitis in the hands, feet and knees.
Junker, Peter, Frederiksen, Louise, Brixen, Kim   +2 more
core   +1 more source