Results 161 to 170 of about 73,323 (250)

Clinical profiles associated with rapidly progressive interstitial lung disease in antisynthetase syndrome: A multicentric cohort study (TYPASS study)

Journal of Internal Medicine, Volume 299, Issue 3, Page 365-380, March 2026.
Abstract Objectives To assess factors associated with rapidly progressive interstitial lung disease (ILD) (RP‐ILD) at time of ILD diagnosis in a multicentric retrospective cohort study of antisynthetase syndrome (ASyS). We used a complementary unsupervised approach, hierarchical clustering, to delineate distinct phenotypes among ASyS patients with ILD.
Maxime Billotte, Thomas Moulinet, Alain Meyer, Houda Camara, Loïs Bolko, Kévin Didier, Sandra Dury, Bernard Bonnotte, Hervé Devilliers, Philippe Bonniaud, Guillaume Beltramo, Julien Campagne, Nadine Magy‐Bertrand, Aurore Chaudier, Simon Valentin, Roland Jaussaud, Paul Decker   +16 more
wiley   +1 more source

Exploring clusters based on ultrasound-detected inflammation in patients with psoriatic arthritis: a post-hoc analysis from the ULTIMATE trial. [PDF]

BMC Musculoskelet Disord
D'Agostino MA, Conaghan PG, Gaillez C, Boers M, Naredo E, Mandl P, Carron P, López-Rdz A, Burgos-Vargas R, Rosa J, Bakewell C, Cazenave T, Bao W, Demanse D, Schett G.   +14 more
europepmc   +1 more source

Synovial Fluid Cell Counts and the Degree of Synovial Tissue Lymphocytic Inflammation in Patients with Rheumatoid Arthritis

ACR Open Rheumatology, Volume 8, Issue 2, February 2026.
Objective The synovial tissue pathotype may determine the treatment response in rheumatoid arthritis (RA); however, biopsies are not widely available. Synovial fluid is a promising tissue surrogate. Our purpose was to compare RA synovial fluid cell counts with histopathology and use synovial fluid to predict tissue inflammation.
Susan M. Goodman, Michael Parides, Solana Cushing, Daniel Ramirez, Edward DiCarlo, Kristine Carandang, Renée A. Davis, Rebecca B. Blank, Laura T. Donlin, Anna Helena Jonsson, Amit Lakhanpal, Bella Mehta, Dana Orange, Melanie H. Smith   +13 more
wiley   +1 more source

3D Bioprinted Human Synovium‐Cartilage Models Mimic Rheumatoid Arthritis Microenvironment and Recapitulate In Vivo Therapeutic Responses

Advanced Materials, Volume 38, Issue 8, 6 February 2026.
This study presents human in vitro rheumatoid arthritis models using chondrocytes recellularized type II collagen scaffold and 3D‐bioprinted Gelatin‐Matrigel hydrogels with fibroblast‐like synoviocytes, pro‐inflammatory macrophages, and protective barrier macrophages, closely recapitulating key rheumatoid arthritis pathological features.
Huiqun Zhou, Zhen Zhang, Yulei Mu, Liang Ma, Xu Hu, Bangheng Liu, Dong‐An Wang   +6 more
wiley   +1 more source

Deep learning and radiomics-based system for early diagnosis of hip synovitis in juvenile idiopathic arthritis. [PDF]

Front Immunol
Kou J, Yin C, Gao Y, Huang D, Yang C, Xiao H.   +5 more
europepmc   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

Nanozyme‐Integrated Hydrogel Targeting AGEs for Diabetic Osteoarthritis Therapy

Advanced Science, Volume 13, Issue 8, 9 February 2026.
A nanozyme–integrated hydrogel (PTC‐MP) exhibiting with mild photothermal effects is constructed, and a “3R” (restrain‐restore‐reinforce) strategy is proposed for diabetic osteoarthritis (DOA) treatment based on advanced glycation end products (AGEs) targeting.
Rui Chen, Yanguo Su, Guiyuan Zhao, Jiaojiao Tao, Qijie Diao, Guangli Xiang, Tianze Jiang, Lu Han, Xia Zhao   +8 more
wiley   +1 more source

Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis [PDF]

, 2005
Baeten, Dominique, BOOTS, AM, CANETE, JD, De Keyser, Filip, De Rycke, Leen, FOELL, D, Kruithof, Elli, ROTH, J, VANDOOREN, BERNARD, Veys, Eric   +9 more
core  

Pigmented Villonodular Synovitis [PDF]

RadioGraphics, 2008
Hillary Warren, Garner, Cedric J, Ortiguera, Raouf E, Nakhleh   +2 more
openaire   +2 more sources

High Bioavailability Resveratrol Delivery System: A Novel Nutritional Strategy for the Prevention and Alleviation of Rheumatoid Arthritis

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
This study developed a high bioavailability resveratrol delivery system for rheumatoid arthritis prevention using solid dispersion. Its oral administration (20 mg·kg−1) doubled bioavailability versus unformulated resveratrol, and the serum biomarkers related to liver and kidney function did not increase, indicating that the preparation has good safety.
Chenchen Yu, Chungang Zhang
wiley   +1 more source