Results 21 to 30 of about 42,836 (210)

The association between patellofemoral grind and synovitis in knee osteoarthritis: data from the osteoarthritis initiative

Frontiers in Medicine, 2023
ObjectivePatellofemoral grind refers to the tender behind the knee cap while contracting the quadriceps muscle during the patellar grind test. The present investigation aims to elucidate the association between patellofemoral grind and synovitis in the ...
Hui Deng, Yongzhong Wu, Zaiwei Fan, Wubing Tang, Jun Tao   +4 more
doaj   +1 more source

Effect of weight loss on knee joint synovitis over 48 months and mediation by subcutaneous fat around the knee: data from the Osteoarthritis Initiative

BMC Musculoskeletal Disorders
Background Obesity influences the development of osteoarthritis via low-grade inflammation. Progression of local inflammation (= synovitis) increased with weight gain in overweight and obese women compared to stable weight.
Maximilian T. Löffler, Chotigar Ngarmsrikam, Paula Giesler, Gabby B. Joseph, Zehra Akkaya, John A. Lynch, Nancy E. Lane, Michael Nevitt, Charles E. McCulloch, Thomas M. Link   +9 more
doaj   +1 more source

Retractions in Rheumatology: Trends, Causes, and Implications for Research Integrity

Arthritis Care &Research, EarlyView.
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley   +1 more source

Serum Matrix Metalloproteinase-3 as a Noninvasive Biomarker of Histological Synovitis for Diagnosis of Rheumatoid Arthritis

Mediators of Inflammation, 2014
Objective. To explore the correlation between matrix metalloproteinase- (MMP-) 3 and histological synovitis in rheumatoid arthritis (RA). Methods. Serum MMP-3 of 62 patients with active RA was detected by ELISA.
Jian-Da Ma, Jing-Jing Zhou, Dong-Hui Zheng, Le-Feng Chen, Ying-Qian Mo, Xiu-ning Wei, Li-Juan Yang, Lie Dai   +7 more
doaj   +1 more source

Blood flow velocity in the anterior humeral circumflex artery and tear size can predict synovitis severity in patients with rotator cuff tears [PDF]

Clinics in Shoulder and Elbow
Background Rotator cuff tears are often associated with synovitis, but the ability of noninvasive ultrasonography to predict the severity of synovitis remains unclear.
Takahiro Machida, Takahiko Hirooka, Akihisa Watanabe, Hinako Katayama, Yuki Matsukubo   +4 more
doaj   +1 more source

Associations of ultrasound-based inflammation patterns with peripheral innate lymphoid cell populations, serum cytokines/chemokines, and treatment response to methotrexate in rheumatoid arthritis and spondyloarthritis.

PLoS ONE, 2021
ObjectivesWe aimed to explore the associations of musculoskeletal inflammation patterns with peripheral blood innate lymphoid cell (ILC) populations, serum cytokines/chemokines, and treatment response to methotrexate in patients with rheumatoid arthritis
Manami Kato, Kei Ikeda, Takahiro Sugiyama, Shigeru Tanaka, Kazuma Iida, Kensuke Suga, Nozomi Nishimura, Norihiro Mimura, Tadamichi Kasuya, Takashi Kumagai, Hiroki Furuya, Taro Iwamoto, Arifumi Iwata, Shunsuke Furuta, Akira Suto, Kotaro Suzuki, Eiryo Kawakami, Hiroshi Nakajima   +17 more
doaj   +1 more source

Validity and diagnostic performance of fluorescence optical imaging measuring synovitis in hand osteoarthritis: baseline results from the Nor-Hand cohort

Arthritis Research & Therapy, 2020
Objective Fluorescence optical imaging (FOI) demonstrates enhanced microcirculation in finger joints as a sign of inflammation. We wanted to assess the validity and diagnostic performance of FOI measuring synovitis in persons with hand OA, comparing it ...
Øystein Maugesten, Alexander Mathiessen, Hilde Berner Hammer, Sigrid Valen Hestetun, Tore Kristian Kvien, Till Uhlig, Sarah Ohrndorf, Ida Kristin Haugen   +7 more
doaj   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

Synovitis in osteoarthritis: the current state of the problem

Современная ревматология, 2021
The article presents current data on synovitis (inflammation of the synovial membrane), which is often the only clinical manifestation of osteoarthritis (OA), and considered to be one of the risk factors for the OA development.
I. S. Dydykina, E. V. Arutyunova, P. S. Kovalenko, E. V. Nikolaeva, A. V. Naumov   +4 more
doaj   +1 more source