Results 171 to 180 of about 43,674 (271)

The molecular landscape of nodular fasciitis: novel USP6 fusions, genomic stability, and an exploratory clinicopathological model – a 20‐year retrospective study

The Journal of Pathology: Clinical Research, Volume 12, Issue 6, November 2026.
Abstract Nodular fasciitis (NF) is a benign myofibroblastic neoplasm characterized by rapid growth and recurrent USP6 rearrangements. Despite its benign nature, NF may exhibit worrisome histologic or clinical features that mimic sarcoma, posing diagnostic challenges.
Kristijan Skok, Maximilian T Buchwald, Maria Anna Smolle, Theresa Godschachner, Andreas Leithner, Christian Viertler, Bernadette Liegl‐Atzwanger   +6 more
wiley   +1 more source

Spatial macrophage-fibroblast interactions in osteoarthritis synovium: inflammatory and fibrotic niches. [PDF]

Front Immunol
Wei H, Lei M, Lao C, Gu R.
europepmc   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, Volume 78, Issue 11, Page 2246-2260, November 2026.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Macrophage lipid metabolism and inflammasome activation in rheumatoid arthritis: emerging mechanisms and therapeutic implications. [PDF]

Front Immunol
Hao H, Zhao H, Dong P, Fan X, Liu J, Wu H, Jia L, Li C, Ao L, Dong Q.   +9 more
europepmc   +1 more source

Association of the ADAMTS14 rs4747096 Polymorphism and C‐Reactive Protein Levels With Knee Osteoarthritis Severity: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims The rs4747096 polymorphism in the ADAMTS14 gene and C‐reactive protein (CRP) levels have been associated with knee osteoarthritis (KOA) severity; however, evidence from Vietnam remains limited. This study aimed to investigate the distribution of rs4747096 genotypes, assess CRP levels, and examine their associations with KOA
Quyen Phuong Tran Cao, Nga Thi Ngoc Pham, Kien Trung Nguyen   +2 more
wiley   +1 more source

Spatial multi‑omics identifies an SPP1+ macrophage‑driven anti‑apoptotic niche in osteoarthritis synovium via the SPP1‑CD44 axis. [PDF]

Int J Mol Med
Gong H, Shen H, Zhang F, Wang W, Zhou S, Wang L, Sun Y.   +6 more
europepmc   +1 more source

Comparative Effects of Photobiomodulation and Platelet‐Rich Plasma on Joint Repair in Rats With Knee Osteoarthritis

Lasers in Surgery and Medicine, Volume 58, Issue 9, Page 802-810, November 2026.
ABSTRACT Objective This study aimed to evaluate whether the combination of photobiomodulation and platelet‐rich plasma therapy provides superior anti‐inflammatory and joint‐protective effects compared to individual treatments in an experimental model of osteoarthritis.
Anne Missrie, Gabriela Saab Sampaio, Vitória Gonzaga Acerbi, Fernando Anselmo, Ítalo Ribeiro Lemes, Ana Laura Martins de Andrade   +5 more
wiley   +1 more source

An epithelial-mesenchymal transition-like synovial stromal-remodeling programme associated with knee osteoarthritis pain: Exploratory transcriptomic discovery and spatial analysis. [PDF]

PLoS One
Ferreira DP, Botan RN, Martins WR, Kessler IM.   +3 more
europepmc   +1 more source

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang, Siwen Wu, Yusi Wang, Die Hu, Li Yang   +4 more
wiley   +1 more source

Updates on intra‐articular corticosteroid administration in horses

Equine Veterinary Education, Volume 38, Issue 11, Page 600-610, November 2026.
Summary Intra‐articular (IA) corticosteroid administration in equine athletes has gained increased attention recently, particularly in racing. Despite widespread corticosteroid use in equine practice for decades, there are still a lack of equine‐specific studies to address key questions related to their use.
K. Tanner, L. Bass, C. Kawcak, L. V. Schnabel, K. L. Hallowell, L. M. Pezzanite   +5 more
wiley   +1 more source