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A Functional Tissue-Engineered Synovium Model to Study Osteoarthritis Progression and Treatment
Tissue Engineering - Part A, 2019 © Copyright 2019, Mary Ann Liebert, Inc., publishers. Little is known about the critical role of the synovium in joint homeostasis and osteoarthritis (OA). We describe a novel in vitro tissue-engineered (TE) model to investigate the structure-function of
Roshan P Shāh +2 more
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Modern Pathology
The synovium is an integral component of synovial joints, as well as extra-articular structures such as the tenosynovium and bursae. This article reviews normal histology and the immunohistochemical profile of the synovium. It also discusses several common and distinctive intra-articular and extra-articular tumors arising in synovium-lined structures ...
Yee Lin Tang +2 more
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The synovium is an integral component of synovial joints, as well as extra-articular structures such as the tenosynovium and bursae. This article reviews normal histology and the immunohistochemical profile of the synovium. It also discusses several common and distinctive intra-articular and extra-articular tumors arising in synovium-lined structures ...
Yee Lin Tang +2 more
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Survival in the rheumatoid synovium
Joint Bone Spine, 2011Joint Bone Spine - In Press.Proof corrected by the author Available online since mercredi 3 aout ...
Dominique, Wachsmann, Jean, Sibilia
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The pathobiology of psoriatic synovium
Current Opinion in Rheumatology, 2008Psoriatic arthritis pathogenesis is incompletely understood and the pathophysiologic role of the synovium is only beginning to be elucidated. Currently, approaches similar to those applied to rheumatoid arthritis are being applied to psoriatic arthritis synovia.Synovitis is being re-examined along with efforts to better characterize the clinical ...
David L, Boyle, Arthur, Kavanaugh
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Control of the synovium in haemophilia
Haemophilia, 1998Summary. Adequate factor substitution is a prerequisite for successful conservative or operative treatment of haemophilic synovitis. Subsequent prophylactic factor substitution can prevent further joint problems in the future. Orthopaedic treatment regimes are dependent on the classification of the synovitis and the stage of the arthropathy.
C. A. Lee +8 more
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International Journal of Molecular Sciences, 2017 Osteoarthritis (OA) is a degenerative disorder characterized by chondrocyte apoptosis and degeneration of articular cartilage resulting in loss of mobility and pain.
John R Matyas +2 more
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Synovium in haemophilic arthropathy
Haemophilia, 1998Summary. Synovium is an essential component of the joint and plays a critical role in maintaining a balance between physiological processes and pathological changes in the joint. Recurrent intra‐articular bleeding as occur in haemophilia induce pathological synovial changes in the joint.
C. A. Lee +12 more
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Mucinous transformation of synovium
Human Pathology, 1982A unique case of mucinous transformation of knee joint synovium associated with recurrent mucinous joint effusions and severe osteoarthritis is presented. The lesion probably represented an extreme pathologic expression of physiologic synoviocytic synthesis of hyaluronic acid.
R L, Goldman, H Z, Klein
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Immunohistochemistry of the Inflamed Synovium
2007The development in the techniques for obtaining synovial tissue biopsy, especially through arthroscopy, have resulted in greater access to high-quality synovial tissue. The use of immunohistochemistry in arthritis research has greatly furthered our understanding of the varied immunological and biochemical pathways involved in inflammatory ...
Martina, Gogarty, Oliver, Fitzgerald
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2016
Synovium is an integrated tissue of the diarthrodial joints that interacts with all the other joint tissues and specifically is important in nourishment and lubrication of the articular cartilage, removal of waste products, and immunological surveillance. Chronic as well as recurrent low-grade synovial inflammation definitely contributes to progression
Floris P. J. G. Lafeber +2 more
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Synovium is an integrated tissue of the diarthrodial joints that interacts with all the other joint tissues and specifically is important in nourishment and lubrication of the articular cartilage, removal of waste products, and immunological surveillance. Chronic as well as recurrent low-grade synovial inflammation definitely contributes to progression
Floris P. J. G. Lafeber +2 more
openaire +1 more source