Results 141 to 150 of about 42,189 (273)

Congruence between the 3 different synteny block reconstructions.

, 2014
An example based on a segment of the Homo sapiens' X chromosome (from coordinates 53,078 to 114,468 kb) and the genome of Mus musculus is presented. The synteny blocks reconstructed by the three tools, SynChro, MCScanX and iADHoRe are represented by red,
Guénola Drillon (539880), Gilles Fischer (4888), Alessandra Carbone (124226)   +2 more
core   +1 more source

Structural Elucidation and Engineering of the (S)‐scoulerine 2‐O‐Methyltransferase Enabling Regioselective Epiberberine Biosynthesis in Coptis chinensis

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4528-4545, July 2026.
ABSTRACT Protoberberine alkaloids are a characteristic group of natural products in Coptis plants known for their notable pharmacological activities. However, the structural similarity and the substrate promiscuity of their biosynthetic enzymes have left the precise synthetic pathways remain unclarified, posing challenges to regulate product formation.
Jun Song, Di Liu, Shi Chen, Yufeng Tan, Siyu Wang, Shihan Li, Yutong Qin, Guofeng Li, Xufang Tian, Lan Yang, Chong Yuan, Junbo Gou, Wei Huang, Shilin Chen, Yifei Liu   +14 more
wiley   +1 more source

Inferring synteny between genome assemblies: a systematic evaluation

, 2018
Background Genome assemblies across all domains of life are being produced routinely. Initial analysis of a new genome usually includes annotation and comparative genomics.
Martin Hunt, Dang Liu, Isheng J Tsai
core   +1 more source

Progress and Challenges in Phylogenomics and Genomics of Lophotrochozoa/Spiralia

Zoologica Scripta, Volume 55, Issue 4, Page 521-544, July 2026.
ABSTRACT Lophotrochozoa is one of the three major bilaterian groups comprising more than half of the bilaterian phyla. Lophotrochozoa includes among others Mollusca, Annelida, Platyhelminthes and Rotifera. Despite representing such a large proportion of animal diversity, they are historically understudied and genomic resources have been scarce. However,
Torsten H. Struck
wiley   +1 more source

Retinoic Acid Informs the Positional Identity of Frontonasal Neural Crest Cells Through Alx Family of Transcription Factors

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Retinoic acid (RA) regulates the positional identity of cranial neural crest cells (CNCCs) through the transcription factors Alx1 and Alx4. Upon receiving RA from the local environment, liganded RAR/RXR heterodimers activate the expression of Alx1 and Alx4, which promote the frontonasal identity of CNCCs and inhibit the first pharyngeal arch identity ...
Shuxuan Wu, Yifan Lu, Yixin Tu, Yuke Xi, Qianxue Wan, Minghui Yue, Huan Liu, Zhaoming Wu   +7 more
wiley   +1 more source

BLADE‐ON‐PETIOLE Genes Enable Genetic Bottleneck Mitigation Through Cross‐Species Repurposing of Floral Persistence Traits

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This study shows that BLADE‐ON‐PETIOLE (BOP) proteins regulate floral abscission and senescence in tomato by interacting with TFAM1 to form transcriptional condensates controlling the ARABIDOPSIS THALIANA HOMEOBOX GENE 1 (ATH1)‐mediated abscission pathway.
Nan Xiao, Qianwen Lyu, Tinghao Zhang, Yupan Zou, Yue Xie, Dandan Yang, Cao Xu, Xiaozhen Huang   +7 more
wiley   +1 more source

Synteny Paths for Assembly Graphs Comparison.

, 2019
Despite the recent developments of long-read sequencing technologies, it is still difficult to produce complete assemblies of eukaryotic genomes in an automated fashion. Genome assembly software typically output assembled fragments (contigs) along with assembly graphs, that encode all possible layouts of these contigs.
Evgeny Polevikov, Mikhail Kolmogorov
openaire   +3 more sources

A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat

Advanced Science, Volume 13, Issue 31, 4 June 2026.
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su, Haosen Yang, Xiaokai Li, Tingting Jiang, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Yan Wang, Li Li, Hongping Zhang, Linjie Wang   +10 more
wiley   +1 more source

Complex History of Organellar Introgression in Nothofagus Trees: Chloroplast and Mitochondrial Capture Facilitated by Natural Selection

Ecology and Evolution, Volume 16, Issue 6, June 2026.
Field photograph of an ancient Nothofagus tree covered with epiphytic lichens in the Patagonian temperate rainforest. This genus serves as a key model for investigating organellar introgression and evolutionary genomics in South America. ABSTRACT Hybridization is widespread across diverse groups of organisms, and in some cases, organellar genomes of ...
Gabriela Narváez, Marie‐Laure Guillemin, Francisco Sepúlveda‐Espinoza, Daly Noll, Rodrigo A. Gutiérrez, Verónica Arana, Nicolás Bellora, Francisco A. Cubillos, Juliana A. Vianna   +8 more
wiley   +1 more source

Still waters run deep in large-scale genome rearrangements of morphologically conservative Polyplacophora

eLife
A major question in animal evolution is how genotypic and phenotypic changes are related, and another is when and whether ancient gene order is conserved in living clades.
Julia D Sigwart, Yunlong Li, Zeyuan Chen, Katarzyna Vončina, Jin Sun   +4 more
doaj   +1 more source