Results 231 to 240 of about 42,189 (273)

Original Synteny

, 1996
. The inference of genome rearrangement requires detailed gene maps of related species. For most multichromosomal species, how-ever, knowledge of chromosomal ssignment of genes outstrips mapping data.
Vincent Ferretti, Joseph H. Nadeau, David Sankoff   +2 more
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The Visual Language of Synteny

OMICS: A Journal of Integrative Biology, 2004
The study of polygenic disorders such as cardiovascular and metabolic diseases requires access to vast amounts of experimental and in silico data. Where animal models of disease are being used, visualization of syntenic genome regions is one of the most important tools supporting data ...
Ela, Hunt, Neil, Hanlon, David P, Leader, Hunter, Bryce, Anna F, Dominiczak   +4 more
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Combinatorics of chromosomal rearrangements based on synteny blocks and synteny packs

Journal of Logic and Computation, 2011
The reconstruction of the history of rearrangements and the reconstruction of ancestral genomes are some of the challenges of bioinformatics today. Many algorithms already exist, treating one or the other question but none treating both. These reconstructions are interdependent and we argue on the interest of treating both problems in parallel to lead ...
Drillon, Guénola, Carbone, Alessandra, Fischer, Gilles   +2 more
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MizBee: A Multiscale Synteny Browser

IEEE Transactions on Visualization and Computer Graphics, 2009
In the field of comparative genomics, scientists seek to answer questions about evolution and genomic function by comparing the genomes of species to find regions of shared sequences. Conserved syntenic blocks are an important biological data abstraction for indicating regions of shared sequences.
Miriah D. Meyer, Tamara Munzner, Hanspeter Pfister   +2 more
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Synteny mapping in river buffalo

Mammalian Genome, 1996
The cosegregation of ten coding loci has been investigated, in a panel of 37 somatic cell hybrids resulting from the fusion of a hamster cell line and river buffalo lymphocytes, by use of Southern hybridization technique. Five syntenic groups, TCRB-PGY3, ASS-ABL, FUCA1P-CRYG, MBP-YES1, and CGN1-ACTA1, previously assigned to cattle as U13, U16, U17, U28,
S M, El Nahas, H A, Oraby, H A, de Hondt, A M, Medhat, M M, Zahran, E R, Mahfouz, A M, Karim   +6 more
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Synteny and Collinearity in Plant Genomes

Science, 2008
Correlated gene arrangements among taxa provide a valuable framework for inference of shared ancestry of genes and for the utilization of findings from model organisms to study less-well-understood systems. In angiosperms, comparisons of gene arrangements are complicated by recurring polyploidy and extensive genome rearrangement.
Haibao, Tang, John E, Bowers, Xiyin, Wang, Ray, Ming, Maqsudul, Alam, Andrew H, Paterson   +5 more
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Genetic Maps and the Use of Synteny

2009
Genetic linkage maps represent the order of known molecular genetic markers along a given chromosome for a given species. This provides an insight into the organisation of a plant genome. In comparative genomics, synteny is the preserved order of genes on chromosomes of related species which results from descent from a common ancestor.
Duran, C., Edwards, D., Batley, J.
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Gene synteny in species of Plasmodium

Molecular and Biochemical Parasitology, 1998
We have attempted to establish the degree of linkage conservation between different species of the malaria parasite Plasmodium. Initially, the chromosome locations of 42 homologous genes were established in parasites from a rodent malaria species and the human malaria parasite P. falciparum.
J M, Carlton, R, Vinkenoog, A P, Waters, D, Walliker   +3 more
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Conserved Synteny and the Zebrafish Genome

2011
Zebrafish offers significant opportunities for the investigation of vertebrate development, evolution, physiology, and behavior and provides numerous models of human disease. Connecting zebrafish phenogenetic biology to that of humans and other vertebrates, however, requires the proper assignment of gene orthologies.
Julian M, Catchen, Ingo, Braasch, John H, Postlethwait   +2 more
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Synteny and Genomic Rearrangements

2012
The concept of synteny, derived from the Greek syn tene (‘same thread’) has come to refer broadly to parallels in gene arrangement in divergent genomes. Gene collinearity, a special case of synteny in which groups of genes occur in largely corresponding orders along the chromosomes of respective genomes, provides valuable information for inferring gene
A. H. Paterson, X. Wang, H. Tang, T. H. Lee   +3 more
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