CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Investigation of earth-abundant photovoltaic material Zn3P2 nanostructures using electron microscopy [PDF]
Urbonavicius Aidas +3 more
doaj +1 more source
Further elaboration of the stereodivergent approach to chaetominine-type alkaloids: synthesis of the reported structures of aspera chaetominines A and B and revised structure of aspera chaetominine B. [PDF]
Lü JF, Wu JF, Ye JL, Huang PQ.
europepmc +1 more source
THE EFFECTS OF LIVER AND PANCREAS EXTRACTS UPON FAT SYNTHESIS AND METABOLISM
E.W. McHenry, Gertrude Gavin
openalex +1 more source
THE SYNTHESIS OF INDOLE-3-ACETYL-
Norman E. Good
openalex +1 more source
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Recent advances in multicomponent synthesis of 5-substituted 1<i>H</i>-tetrazoles from aldehydes: catalytic methods and green chemistry approaches. [PDF]
Hsu CY +9 more
europepmc +1 more source
A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker +3 more
wiley +1 more source
Cost Evidence Yields the Viability of Metal Oxides Synthesis Routes. [PDF]
Gkika DA, Kyzas GZ.
europepmc +1 more source

