Results 1 to 10 of about 116,777 (208)

Antischistosomal Activity of 1,4-Dihydropyridines

Drugs and Drug Candidates
Background/Objectives: Recent reports have demonstrated the antiparasitic activity of 1,4-dihydropyridine (1,4-DHPs). This study aimed to assess the in vitro antischistosomal activity of 24 1,4-DHPs against Schistosoma mansoni adult worms.
Thaís A. S. Oliveira, Matheus H. M. Zago, Larissa G. Maciel, Yan R. Robles, Lizandra G. Magalhães, Antônio E. M. Crotti   +5 more
doaj   +2 more sources

The accelerated preparation of 1,4-dihydropyridines using microflow reactors

, 2014
The synthesis of 1,4-dihydropyridines was performed in a continuous-flow microreactor. Elevated temperatures accelerated the reaction rate significantly allowing the reaction to be finished in minutes (6–11 min).
Timothy Noel, Baraldi, Patricia Tambarussi, Hessel, Volker, Patricia Tambarussi Baraldi, Wang, Q., Tambarussi Baraldi, P., Wang, Qi, Volker Hessel, Noel, T., Qi Wang, Noël, Timothy, Hessel, V.   +11 more
core   +1 more source

Antioxidant activity of 2,6-dimethyl-3,5-dialkoxycarbonyl-1,4-dihydropyridines in metal-ion catalyzed lipid peroxidation

Czech Journal of Food Sciences, 2001
Antioxidants with 1,4-dihydropyridine structure were investigated as a less harmful alternative to synthetic phenolic antioxidants in liposomes under conditions simulating food storage.
G. Tirzitis, D. Tirzite, Z. Hyvonen
doaj   +1 more source

1,4-Dihydropyridines: Reactivity of nitrosoaryl and nitroaryl derivatives with alkylperoxyl radicals and ABTS radical cation [PDF]

, 2004
In the present paper, a direct quenching of radical species by a number of synthesized nitrosoaryl 1,4-dihydropyridines and their parent nitroaryl 1,4-dihydropyridines was determined in aqueous media at pH 7.4. These two series of compounds were compared
Squella Serrano, Juan, López Alarcón, Camilo, Núñez Vergara, Luis, Valenzuela, V., Camargo Grandón, Rodrigo, Santander, P.   +5 more
core  

Regio and enantioselective synthesis of 4-carbomethoxymethyl-1,4 dihydropyridines

, 1994
Regio and enantioselective 1,4 addition of ethoxyvinyl copper reagent on a pyridine bearing in position 3 a chiral aminal is described.
Raussou, Sabine, Alexakis, Alexandre, Sabine Raussou, Alexandre Alexakis, Gosmini, Romain, Romain Gosmini, Pierre Mangeney, Mangeney, Pierre, Monique Commerçon, Commerçon, Monique   +9 more
core   +1 more source

Synthesis of new 4-nitrosophenyl-1,4-dihydropyridines of pharmacological interest [PDF]

, 2003
The synthesis and characterization of a series of 4-nitrosophenyl-1.4-dihydropyridines derived from the respective nitro compounds of pharmacological interest is described.
Squella Serrano, Juan, Núñez Vergara, Luis, Santander Gutiérrez, Ingrid Paola, Navarrete Encina, Patricio   +3 more
core  

De Novo Synthesis of 1,4-Dihydropyridines and Pyridines

, 2012
An efficient and general method for the synthesis of 1,4-dihydropyridines and pyridines based on a lithiation/isomerization/intramolecular carbolithiation sequence is reported. This procedure provides an efficient, divergent, and straightforward entry to
Rammah, B. Mohamed, Rammah, M. Mohamed, Couty, François, Evano, Gwilherm, gati, Wafa   +4 more
core   +1 more source

De Novo Synthesis of 1,4-Dihydropyridines and Pyridines

, 2016
An efficient and general method for the synthesis of 1,4-dihydropyridines and pyridines based on a lithiation/isomerization/intramolecular carbolithiation sequence is reported. This procedure provides an efficient, divergent, and straightforward entry to
Gwilherm Evano (1355874), François Couty (1819657), Wafa Gati (1944688), Mohamed B. Rammah (1819654), Mohamed M. Rammah (1819666)   +4 more
core   +1 more source

Rearrangement of 3,5-dicyano-1,4-dihydropyridines to densely functionalized cyclopentadienes

, 2008
3,5-Dicyano-1,4-dihydropyridines underwent ring contraction to give functionalized cyclopentadienes upon treatment with trifluoroacetic anhydride. © 2008 Elsevier Ltd.
Ponticelli, Fabio, Fusi, Stefania, Ventura, Antonio, Adamo, Mauro F. A.   +3 more
core   +1 more source

Facile, Regioselective [4 + 2] Cycloaddition Involving 1-Aryl-4-phenyl-1-azadienes and Allenic Esters:  An Efficient Route to Novel Substituted 1-Aryl-4-phenyl-1,4-dihydropyridines

, 2016
1-Aryl-4-phenyl-1-azadienes undergo facile, regioselective [4 + 2] cycloaddition to the C2,C3 π-bond of allenic esters in refluxing benzene, and the formed adducts undergo a 1,3-H shift to afford novel 2-alkyl-1-aryl-3-ethoxycarbonyl-4-phenyl-1,4 ...
Sumanjit Kaur (3063594), Navdeep K. Girdhar (3063585), Shiv Kumar (634406), Ashish Kapoor (511738), Alka Marwaha (2381389), Satish Sachar (3063591), Kamal Kumar (91852), M. P. S. Ishar (3063588)   +7 more
core   +1 more source