Results 1 to 10 of about 5,082 (203)

Synthesis, spectroscopic characterization, X-ray structure, and DFT calculations of some new 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxamides. [PDF]

open access: yesPLoS ONE, 2014
A series of novel 1,4-dihydro-2,6- dimethyl-3,5-pyridinedicarboxamides were synthesized and characterized by infrared absorption spectrum (IR), proton nuclear magnetic resonance (1H NMR), elemental analysis, ultraviolet spectrum (UV), and fluorescence ...
Yi Li   +4 more
doaj   +1 more source

Sirtuin functions and modulation: from chemistry to the clinic [PDF]

open access: yes, 2016
Sirtuins are NAD+ -dependent histone deacetylases regulating important metabolic pathways in prokaryotes and eukaryotes and are involved in many biological processes such as cell survival, senescence, proliferation, apoptosis, DNA repair, cell ...
Altucci, Lucia   +9 more
core   +2 more sources

Design and synthesis of novel 4-substituted 1,4-dihydropyridine derivatives as hypotensive agents

open access: yesJournal of Saudi Chemical Society, 2016
Calcium-channel blockers have an important role in the treatment of several cardiovascular disorders. Derivatives of 1,4-dihydropyridines are one of the most potent calcium antagonists.
Prasanna A. Datar, Pratibha B. Auti
doaj   +1 more source

Sodium Hypochlorite-Dowex 1X8-200: A Convenient Oxidizing Reagant [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2002
The polymer supported hypochlorite ion is a facile selective oxidizing agent for the oxidation of various alcohols to aldehydes and ketones. Similarly is successfully oxidizes various Hantzsch type 1,4- dihydropyridines to corresponding pyridines.
Mahammad Mahmoodi Hashemi   +1 more
doaj  

Genotoxic and genoprotective effects of 1,4-dihydropyridine derivatives: a brief review

open access: yesArhiv za Higijenu Rada i Toksikologiju, 2023
This review summarises current knowledge about the genotoxic and genoprotective effects of 1,4-dihydropyridines (DHP) with the main focus on the water-soluble 1,4-DHPs.
Leonova Elina   +9 more
doaj   +1 more source

Synthesis of arylpiridines with us on bifuntional catalysts Me/SiO2-SO3H (Me= Au, Ir, Pt) [PDF]

open access: yes, 2016
Se estudió la reacción multicomponente de Hantzsch para la obtención de compuestos derivados de la familia 2-arilpiridinas, usando catalizadores bifuncionales tipo Me/SiO2-SO3H (Me = Au, Pt, Ir). Los catalizadores se caracterizaron por distintas técnicas
Martinez, José   +4 more
core  

Chemoselective Protection and Deprotection of Aldehydes Using Solid Supported Reagent (Silica Chloride) under Solvent-Free Conditions [PDF]

open access: yes, 2011
Silica chloride, a heterogeneous catalyst, has been found to be an efficient catalyst for the protection of aldehydes as acylals under solvent-free conditions, and deprotection of acylals to aldehydes in methanol as a solvent occurred. The reaction takes
Banditadatta, ., Pasha, M.A.
core   +1 more source

Structural investigations of the regio- and enantioselectivity of lipases [PDF]

open access: yes, 1998
Although lipases are widely applied for the stereospecific resolution of racemic mixtures of esters, the atomic details of the factors that are responsible for their stereospecificity are largely obscure. We determined the X-ray structures of Pseudomonas
Bando   +38 more
core   +2 more sources

Nucleophilic dearomatization of 4-aza-6-nitrobenzofuroxan by CH acids in the synthesis of pharmacology-oriented compounds

open access: yesBeilstein Journal of Organic Chemistry, 2017
4-Aza-6-nitrobenzofuroxan (ANBF) reacts with 1,3-dicarbonyl compounds and other CH acids to give carbon-bonded 1,4-adducts – 1,4-dihydropyridines fused with furoxan ring.
Alexey M. Starosotnikov   +5 more
doaj   +1 more source

Antioxidant activity of 2,6-dimethyl-3,5-dialkoxycarbonyl-1,4-dihydropyridines in metal-ion catalyzed lipid peroxidation

open access: yesCzech Journal of Food Sciences, 2001
Antioxidants with 1,4-dihydropyridine structure were investigated as a less harmful alternative to synthetic phenolic antioxidants in liposomes under conditions simulating food storage.
G. Tirzitis, D. Tirzite, Z. Hyvonen
doaj   +1 more source

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