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Synthesis of 1,4-Dihydropyridine Derivatives Under Aqueous Media [PDF]

open access: yesE-Journal of Chemistry, 2010
An environmental friendly synthesis of 1,4-dihydropyridine derivatives was developed by the one-pot reaction of aldehydes, ethyl acetoacetate and ammonia in water under refluxing conditions.
Adeleh Moshtaghi Zonouz   +1 more
doaj   +2 more sources

Diethyl 4-(1H-indol-3-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

open access: yesIUCrData, 2019
In the title compound, C21H24N2O4, the 1,4-dihydropyridine ring adopts a very flattened boat conformation, with the 3-pyridine substituent in an axial orientation.
Ji Hye Lee, Dongsoo Koh
doaj   +2 more sources

1,4-Dihydropyridine Anions as Potent Single-Electron Photoreductants. [PDF]

open access: yesOrg Lett
We report the use of simple 1,4-dihydropyridine anions as a general platform for promoting single-electron photoreductions. In the presence of a mild base, 1,4-dihydropyridines were shown to effectively promote the hydrodechlorination and borylation of ...
Gallage PC, McKee MG, Pitre SP.
europepmc   +2 more sources

Green synthesis, molecular docking and anticancer activity of novel 1,4-dihydropyridine-3,5-Dicarbohydrazones under grind-stone chemistry

open access: yesGreen Chemistry Letters and Reviews, 2020
The reaction of 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarbohydrazide with variety of carbonyl compounds such as substituted benzaldehydes, cycloalkanones and hetero-cyclic ketones under grinding method under catalyst- and solvent-free ...
Sobhi M Gomha   +2 more
exaly   +2 more sources

Synthesis and assessment of the cytotoxic effect of some of 1,4-dihydropyridine derivatives which contain azole moiety [PDF]

open access: yesJournal of the Serbian Chemical Society, 2021
A number of 1,4-dihydropyridine derivatives (9a–d, 10a–d and 11a–d) were designed and synthesized by the reaction of 1,3,4-oxadiazole-5-thiones and 1,2,4-triazole-5-thiones to 2,6-dibromomethyl-3,5-diethoxycarbonyl-4-(3- -nitrophenyl)-1,4-dihydropyridine.
Ghoorbannejad Saeed   +2 more
doaj   +1 more source

Synthesis and Characterisation of 1,1′-{[3,5-Bis(dodecyloxy-carbonyl)-4-(thiophen-3-yl)-1,4-dihydropyridine-2,6-diyl]bis-(methylene)}bis(pyridin-1-ium) Dibromide

open access: yesMolbank, 2021
In the present work, construction of double-charged cationic amphiphilic 1,1′-{[3,5-bis(dodecyl¬oxy-carbonyl)-4-(thiophen-3-yl)-1,4-dihydropyridine-2,6-diyl]bis-(methylene)}bis(pyridin-1-ium) dibromide (7) was performed in four steps.
Martins Rucins   +6 more
doaj   +1 more source

Data for the synthesis and characterisation of 2,6-di(bromomethyl)-3,5-bis(alkoxycarbonyl)-4-aryl-1,4-dihydropyridines as important intermediates for synthesis of amphiphilic 1,4-dihydropyridines

open access: yesData in Brief, 2020
This data file describes the synthetic protocol for preparation of the original 2,6-di(bromomethyl)-3,5-bis(alkoxycarbonyl)-4-aryl-1,4-dihydropyridines. In total, 6 unpublished compounds were obtained and characterised.
Martins Rucins   +6 more
doaj   +1 more source

Study of novel 1,4-dihydropyridine derivatives as prospective anti-inflammatory remedies: a randomised controlled trial

open access: yesКубанский научный медицинский вестник, 2022
Background. Over the past decades, scientific community is motivated on finding new anti-inflammatory agents with a safe and high-effective profile to manage pathology.Objectives. A study of the anti-inflammatory action of novel compounds, 1,4-dihydropyridine
E. Yu. Bibik   +9 more
doaj   +1 more source

Data for the cytotoxicity, self-assembling properties and synthesis of 4-pyridinium-1,4-dihydropyridines

open access: yesData in Brief, 2020
In this data file the synthetic procedures for preparation of the original 4-pyridinium-1,4-dihydropyridines (4-Py-1,4-DHP) and their parent compounds – dialkyl 2,6-dimethyl-4-(3-pyridyl)-1,4-dihydropyridine-3,5-dicarboxylates were described. In total, 5
Klavs Pajuste   +8 more
doaj   +1 more source

1,4-Dihydropyridine Anions as Potent Single-Electron Photoreductants

open access: yes, 2023
Organic anions offer a promising route for promoting difficult single-electron reductions, owing to their strongly reducing excit-ed states that can be accessed under visible light irradiation.
Spencer, Pitre   +2 more
core   +1 more source

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